Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 2979770..2980318 Replicon chromosome
Accession NZ_CP032312
Organism Pannonibacter phragmitetus BB

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag P874_RS13580 Protein ID WP_094461896.1
Coordinates 2980025..2980318 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag P874_RS13575 Protein ID WP_094462056.1
Coordinates 2979770..2980021 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P874_RS13555 2974798..2975496 - 699 WP_094461893.1 aspartate/glutamate racemase family protein -
P874_RS13560 2975616..2976227 + 612 WP_094461894.1 pyridoxamine 5'-phosphate oxidase family protein -
P874_RS13565 2976502..2978547 + 2046 WP_094462055.1 M3 family metallopeptidase -
P874_RS13570 2978820..2979536 + 717 WP_162936379.1 DUF4145 domain-containing protein -
P874_RS13575 2979770..2980021 + 252 WP_094462056.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
P874_RS13580 2980025..2980318 + 294 WP_094461896.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P874_RS25270 2980586..2980888 + 303 WP_162936380.1 hypothetical protein -
P874_RS13585 2981157..2981498 + 342 WP_208997565.1 DUF423 domain-containing protein -
P874_RS13590 2981540..2982295 - 756 WP_094461898.1 SDR family oxidoreductase -
P874_RS13595 2982512..2983336 - 825 WP_094461899.1 S-formylglutathione hydrolase -
P874_RS13600 2983347..2984474 - 1128 WP_050472784.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(6-62)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11197.88 Da        Isoelectric Point: 5.1167

>T111645 WP_094461896.1 NZ_CP032312:2980025-2980318 [Pannonibacter phragmitetus BB]
MGFQLSLEAEEDIIGIAETGLRLFGIEQARRYHDQLFDLFDLIAANPQLARERPELTPPMRIYPFKAHLIIYRITEGGDI
LIVRIRHGHEDWATLPS

Download         Length: 294 bp

>T111645 NZ_CP032312:2980025-2980318 [Pannonibacter phragmitetus BB]
ATGGGCTTTCAGCTGTCCCTTGAAGCGGAAGAGGATATTATCGGCATTGCCGAAACAGGCTTACGCCTTTTTGGGATTGA
ACAGGCGAGAAGATACCATGACCAACTGTTCGATCTGTTTGACCTGATCGCGGCAAATCCCCAGCTGGCAAGAGAACGCC
CGGAATTGACGCCGCCCATGCGCATATATCCATTCAAGGCGCACCTGATCATCTACAGGATTACCGAAGGCGGAGATATT
CTCATTGTCCGGATAAGGCACGGGCATGAGGACTGGGCAACTTTGCCGTCCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9250.41 Da        Isoelectric Point: 5.8450

>AT111645 WP_094462056.1 NZ_CP032312:2979770-2980021 [Pannonibacter phragmitetus BB]
MVTMTVSLPDPVKEWVEEQARTGRYANASDYVLDLIRKDQERSNKIAAMQRHVDEGLQSGLGSRSKEELFEAALTRTAAL
RGG

Download         Length: 252 bp

>AT111645 NZ_CP032312:2979770-2980021 [Pannonibacter phragmitetus BB]
ATGGTGACCATGACTGTATCCTTGCCAGATCCCGTGAAGGAATGGGTGGAGGAGCAGGCCCGCACCGGCCGTTATGCGAA
TGCGAGCGACTATGTGCTTGATCTGATCCGCAAGGATCAGGAGCGCAGCAACAAGATTGCGGCCATGCAGCGCCATGTGG
ACGAAGGTCTGCAGAGCGGCTTGGGCAGCCGCTCGAAAGAAGAGTTGTTCGAGGCCGCGCTGACACGGACAGCAGCACTG
CGCGGCGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References