Detailed information of TA system TA111644

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 2466870..2467672
• Replicon: chromosome
• Accession: NZ_CP032312
• Organism: Pannonibacter phragmitetus BB

Toxin (Protein)

• Gene name: TacT3
• Uniprot ID: -
• Locus tag: P874_RS11375
• Protein ID: WP_094461732.1
• Coordinates: 2466870..2467397 (-)
• Length: 176 a.a.

Antitoxin (Protein)

• Gene name: TacA3
• Uniprot ID: -
• Locus tag: P874_RS11380
• Protein ID: WP_094461733.1
• Coordinates: 2467394..2467672 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P874_RS11350	2462612..2463946	-	1335	WP_058899767.1	aspartate aminotransferase family protein	-
P874_RS11355	2464366..2465034	+	669	WP_094461728.1	TetR/AcrR family transcriptional regulator	-
P874_RS11360	2465031..2465753	+	723	WP_094461729.1	TetR family transcriptional regulator C-terminal domain-containing protein	-
P874_RS11365	2465875..2466132	-	258	WP_094461730.1	hypothetical protein	-
P874_RS11370	2466382..2466816	+	435	WP_208999648.1	aminoacyl-tRNA hydrolase	-
P874_RS11375	2466870..2467397	-	528	WP_094461732.1	GNAT family N-acetyltransferase	Toxin
P874_RS11380	2467394..2467672	-	279	WP_094461733.1	DUF1778 domain-containing protein	Antitoxin
P874_RS11385	2467729..2468325	-	597	WP_094461734.1	YitT family protein	-
P874_RS11390	2468346..2469596	-	1251	WP_094461735.1	FAD-binding oxidoreductase	-
P874_RS11395	2469717..2470061	-	345	WP_058899773.1	RidA family protein	-
P874_RS11400	2470065..2470826	-	762	WP_094461736.1	TetR/AcrR family transcriptional regulator	-
P874_RS11405	2470834..2472354	-	1521	WP_162936360.1	amidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (6-87)

Sequences

Toxin

Protein

• Length: 176 a.a.
• Molecular weight: 18911.69 Da
• Isoelectric Point: 8.2880

>T111644 WP_094461732.1 NZ_CP032312:c2467397-2466870 [Pannonibacter phragmitetus BB]
VNLPGWHEEPVAKAHDRDAFDCGDADLNVFLRRYARQSHEMNASKTFCAISDAQPNRVLGFYTLAPASVDYAEVPSHMTR
RIARHEVPGFRLARLAVDVSMAGKGLGGQLLAAAALRCLRLANDGGGLLLIIDAKSDRAASWYRSFGAEPLQDSPLTLVI
PLATFAPGLKTKGLL

Nucleotide

• Length: 528 bp

>T111644 NZ_CP032312:c2467397-2466870 [Pannonibacter phragmitetus BB]
GTGAACCTGCCCGGCTGGCATGAGGAGCCTGTGGCGAAGGCTCATGACCGCGACGCCTTTGATTGCGGGGATGCAGACCT
CAATGTCTTCCTGCGGCGCTATGCACGCCAAAGCCATGAGATGAACGCCTCCAAGACCTTCTGTGCAATTTCCGATGCGC
AGCCCAACCGCGTTCTCGGTTTCTACACACTCGCTCCGGCCAGTGTCGACTATGCCGAGGTTCCCTCTCACATGACACGG
CGGATTGCCCGGCATGAAGTGCCCGGCTTCCGTCTGGCCCGGCTGGCCGTCGATGTTTCCATGGCGGGCAAGGGTCTTGG
CGGCCAGTTGCTGGCAGCTGCCGCCCTCAGATGCCTGCGCCTTGCAAATGACGGTGGTGGCCTGTTGCTGATCATCGATG
CCAAATCGGACCGGGCAGCGTCCTGGTACCGGAGCTTTGGCGCCGAGCCCTTGCAGGACAGCCCCCTGACGCTGGTCATT
CCACTGGCAACCTTTGCCCCGGGCCTCAAAACCAAAGGCCTTCTATAG

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10135.65 Da
• Isoelectric Point: 6.4724

>AT111644 WP_094461733.1 NZ_CP032312:c2467672-2467394 [Pannonibacter phragmitetus BB]
MPRAAVEDNERMNLRIPAEVKAKLVRAAALKHTDLTSFVTQTALREAEAVIEEAESLKASSRDFTRIMTLLENPPKANDR
LAAAIHALPESL

Nucleotide

• Length: 279 bp

>AT111644 NZ_CP032312:c2467672-2467394 [Pannonibacter phragmitetus BB]
ATGCCCAGGGCCGCTGTTGAAGACAATGAACGCATGAACCTGCGCATCCCGGCGGAGGTGAAGGCAAAGCTTGTCCGTGC
GGCAGCCCTGAAGCACACGGACCTTACCAGCTTCGTCACGCAAACGGCTTTGCGTGAAGCCGAAGCCGTGATTGAAGAGG
CTGAATCCCTCAAGGCCTCCAGCCGGGATTTCACGAGGATCATGACGCTTCTTGAAAATCCGCCCAAGGCAAATGACCGT
CTGGCTGCGGCCATCCACGCTCTGCCTGAATCATTGTGA