Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 2303113..2303644 Replicon chromosome
Accession NZ_CP032312
Organism Pannonibacter phragmitetus BB

Toxin (Protein)


Gene name stbE Uniprot ID A0A0L0J552
Locus tag P874_RS10605 Protein ID WP_050471640.1
Coordinates 2303348..2303644 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0L0J5B6
Locus tag P874_RS10600 Protein ID WP_050471641.1
Coordinates 2303113..2303358 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P874_RS10585 2299208..2300782 + 1575 WP_208982589.1 glucan biosynthesis protein -
P874_RS10590 2300815..2301174 + 360 WP_050471643.1 hypothetical protein -
P874_RS10595 2301180..2302973 + 1794 WP_094461666.1 glucans biosynthesis glucosyltransferase MdoH -
P874_RS10600 2303113..2303358 + 246 WP_050471641.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
P874_RS10605 2303348..2303644 + 297 WP_050471640.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P874_RS10610 2303751..2304053 + 303 WP_050471639.1 hypothetical protein -
P874_RS10615 2304081..2304335 - 255 WP_208977399.1 hypothetical protein -
P874_RS25215 2304471..2307065 + 2595 WP_162936348.1 hypothetical protein -
P874_RS10630 2307062..2307388 + 327 WP_208999580.1 EscU/YscU/HrcU family type III secretion system export apparatus switch protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-69)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11166.90 Da        Isoelectric Point: 10.5956

>T111643 WP_050471640.1 NZ_CP032312:2303348-2303644 [Pannonibacter phragmitetus BB]
MSYELQFLPSALKEWNKLGATIRAQLRKKLAERLQNPRVPGDALHGLQDHYKIKLRSAGYRLVYRVDDLVVTVTVVAVGR
RDSSEVYKDASDRRKGLA

Download         Length: 297 bp

>T111643 NZ_CP032312:2303348-2303644 [Pannonibacter phragmitetus BB]
ATGAGCTATGAGCTTCAGTTTCTACCTTCCGCGTTGAAGGAATGGAACAAACTGGGCGCAACGATCCGGGCTCAGCTGCG
CAAGAAACTGGCCGAGCGCCTGCAGAACCCGCGTGTTCCGGGCGATGCTCTGCATGGCCTGCAGGACCATTACAAGATCA
AGCTCCGCAGCGCAGGCTACCGGCTTGTCTACCGTGTCGATGACCTCGTGGTAACTGTCACCGTGGTGGCCGTTGGCCGC
CGTGACAGCAGTGAAGTCTACAAGGACGCATCAGACAGGCGGAAGGGTCTGGCCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8967.38 Da        Isoelectric Point: 4.5960

>AT111643 WP_050471641.1 NZ_CP032312:2303113-2303358 [Pannonibacter phragmitetus BB]
MQRIEAKVAVSVSELKKSPSAVLEQAQGETVAVLNHNRIMAYMVPASVFETMIERLDDLELVKVIESRAGETPVRVSLDE
L

Download         Length: 246 bp

>AT111643 NZ_CP032312:2303113-2303358 [Pannonibacter phragmitetus BB]
ATGCAGCGTATCGAGGCGAAAGTAGCCGTCAGCGTTTCCGAACTGAAGAAAAGCCCTTCCGCTGTGCTGGAACAGGCGCA
GGGAGAGACGGTTGCTGTGCTCAATCACAACCGCATCATGGCTTACATGGTGCCAGCCAGCGTGTTCGAGACGATGATCG
AGCGTCTGGATGATCTGGAGCTGGTCAAGGTCATCGAGAGCCGTGCCGGTGAGACACCGGTCCGGGTTTCACTTGATGAG
CTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0L0J552

Antitoxin

Source ID Structure
AlphaFold DB A0A0L0J5B6

References