111642

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2006059..2007089 Replicon chromosome
Accession NZ_CP032312
Organism Pannonibacter phragmitetus BB

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag P874_RS09320 Protein ID WP_094462904.1
Coordinates 2006520..2007089 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID A0A0L0IUA3
Locus tag P874_RS09315 Protein ID WP_050474753.1
Coordinates 2006059..2006523 (+) Length 155 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P874_RS09290 2001480..2002124 - 645 WP_058900145.1 hypothetical protein -
P874_RS09295 2002439..2004454 - 2016 WP_208999574.1 5'-nucleotidase C-terminal domain-containing protein -
P874_RS09300 2004611..2005339 - 729 WP_208999575.1 lipoyl(octanoyl) transferase LipB -
P874_RS09305 2005483..2005749 + 267 WP_050474723.1 flagellar motor switch protein FliN -
P874_RS09310 2005688..2005912 - 225 WP_094463004.1 pentapeptide repeat-containing protein -
P874_RS09315 2006059..2006523 + 465 WP_050474753.1 helix-turn-helix domain-containing protein Antitoxin
P874_RS09320 2006520..2007089 + 570 WP_094462904.1 PIN domain-containing protein Toxin
P874_RS09330 2007534..2007851 + 318 WP_050474725.1 YARHG domain-containing protein -
P874_RS09335 2008083..2009498 + 1416 WP_162936467.1 magnesium transporter -
P874_RS09340 2009590..2009988 + 399 WP_094462906.1 MerR family DNA-binding transcriptional regulator -
P874_RS09345 2010015..2010461 + 447 WP_050474728.1 PaaI family thioesterase -
P874_RS09350 2010487..2010936 + 450 WP_050474729.1 GNAT family N-acetyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-113)

Antitoxin

(81-126)


Sequences


Toxin        


Download         Length: 190 a.a.        Molecular weight: 21071.45 Da        Isoelectric Point: 6.7452

>T111642 WP_094462904.1 NZ_CP032312:2006520-2007089 [Pannonibacter phragmitetus BB]
VSQARVLLDANVLYPAPLRDLLLQLAVSDVIIAAWTERIHCEWIEALLRRQPWRERRALERTRDLMNEAISDCLIHGYEK
IIPSLVLPDPDDRHVLAAAIAGRCGVILTHNTRDFPPEALAPHGIEAQNPDEFLLAHLSRVPGLFCAAVKKVRSRLKTPP
LDPGEYLAVLRRQGLIETAAGLETFASSI

Download         Length: 570 bp

>T111642 NZ_CP032312:2006520-2007089 [Pannonibacter phragmitetus BB]
GTGAGTCAGGCTCGGGTTCTGCTCGACGCAAATGTTCTTTACCCGGCCCCACTGCGGGATCTGTTGCTCCAGCTTGCCGT
TTCGGACGTTATTATTGCGGCATGGACCGAACGCATACACTGCGAGTGGATTGAGGCGCTGTTGCGCAGGCAGCCGTGGC
GCGAGCGCCGGGCGCTTGAGCGGACAAGGGACCTTATGAATGAGGCAATAAGCGACTGCCTCATTCATGGATACGAGAAA
ATTATCCCCTCGCTTGTCTTGCCTGACCCGGATGACCGCCATGTGCTTGCGGCGGCGATTGCCGGGCGCTGTGGCGTTAT
CCTGACACATAACACCAGGGATTTTCCGCCAGAGGCGCTGGCTCCTCATGGCATTGAAGCGCAAAATCCGGACGAGTTCC
TGCTCGCGCACCTTTCTCGTGTGCCGGGACTGTTCTGCGCTGCAGTGAAAAAAGTGCGGTCACGCCTGAAGACGCCGCCG
CTGGATCCTGGTGAATATCTGGCTGTTCTGAGGCGTCAGGGGCTGATCGAAACGGCAGCCGGACTGGAGACCTTTGCCAG
CTCGATCTGA

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 17093.81 Da        Isoelectric Point: 8.0758

>AT111642 WP_050474753.1 NZ_CP032312:2006059-2006523 [Pannonibacter phragmitetus BB]
MTFPVYSQRRPTRQEAAVARVSEQALACHARDGAPLKLRVTGHEETEVVELPAGAVTLLMEILKAMAAGQGVTVVPDDAE
LTTVQAAELLNVSRPFLIKLLEEGKIPHRKVGKHRRALMQDVIAYKRIMDRRREEILDQLVAEAQEQGMGYGAR

Download         Length: 465 bp

>AT111642 NZ_CP032312:2006059-2006523 [Pannonibacter phragmitetus BB]
ATGACATTCCCGGTATACAGTCAGCGCAGGCCCACCCGGCAGGAGGCAGCGGTTGCACGCGTTTCCGAGCAGGCCCTTGC
CTGCCACGCGCGTGACGGAGCGCCACTGAAATTGCGCGTAACGGGGCACGAAGAGACAGAGGTGGTGGAACTGCCGGCAG
GCGCAGTTACTCTGCTGATGGAAATTCTCAAGGCCATGGCGGCGGGGCAGGGGGTGACGGTTGTTCCCGATGATGCCGAG
TTGACCACGGTACAGGCTGCAGAGCTTCTGAATGTGTCCCGGCCCTTCCTGATCAAGCTCCTGGAGGAAGGTAAAATTCC
CCATCGCAAGGTCGGGAAGCACCGGCGGGCGCTCATGCAGGACGTGATTGCTTACAAGCGCATCATGGATCGCAGGCGGG
AGGAAATCCTCGACCAACTGGTTGCCGAAGCGCAGGAACAGGGCATGGGATACGGCGCAAGGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A0L0IUA3

References