Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 878688..879277 Replicon chromosome
Accession NZ_CP032312
Organism Pannonibacter phragmitetus BB

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag P874_RS04190 Protein ID WP_094462423.1
Coordinates 878688..878981 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag P874_RS04195 Protein ID WP_050472155.1
Coordinates 878984..879277 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P874_RS04165 874135..875010 - 876 WP_119396592.1 allophanate hydrolase subunit 1 -
P874_RS04170 875010..876392 - 1383 WP_094462425.1 acetyl-CoA carboxylase biotin carboxylase subunit -
P874_RS04175 876389..876631 - 243 WP_119396593.1 biotin carboxyl carrier domain-containing protein -
P874_RS04180 876628..877425 - 798 WP_019963362.1 5-oxoprolinase subunit PxpA -
P874_RS04185 877714..878613 + 900 WP_050472156.1 LysR family transcriptional regulator -
P874_RS04190 878688..878981 + 294 WP_094462423.1 addiction module antitoxin RelB Toxin
P874_RS04195 878984..879277 + 294 WP_050472155.1 putative addiction module antidote protein Antitoxin
P874_RS04200 879365..880789 - 1425 WP_094462422.1 aspartate aminotransferase family protein -
P874_RS04205 881049..881558 + 510 WP_050472153.1 RNA polymerase sigma factor -
P874_RS04210 881665..882717 + 1053 WP_094462420.1 FecR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Uncharacterized protein HI1420

(7-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10905.76 Da        Isoelectric Point: 10.5155

>T111641 WP_094462423.1 NZ_CP032312:878688-878981 [Pannonibacter phragmitetus BB]
MIEVRQTAVFRGWFAELKDLRARSRIARRIAAVQSGLLGDVKFFDGIGELRIDYGPGYRVYFVRKGAVVIILLCGGDKGS
QARDIRKARMMAADLEE

Download         Length: 294 bp

>T111641 NZ_CP032312:878688-878981 [Pannonibacter phragmitetus BB]
ATGATCGAAGTCCGCCAGACAGCCGTCTTTCGCGGCTGGTTTGCTGAGTTGAAAGACTTGCGCGCCCGAAGCCGGATCGC
CAGACGGATTGCCGCCGTGCAAAGTGGTTTATTGGGCGATGTAAAATTCTTCGATGGCATAGGCGAGCTTCGTATCGATT
ATGGCCCGGGCTATCGCGTTTATTTCGTCCGCAAGGGTGCGGTGGTGATCATCCTGCTGTGCGGGGGAGACAAAGGCAGC
CAGGCCCGCGATATCCGCAAGGCCAGGATGATGGCTGCGGATCTGGAGGAATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10114.61 Da        Isoelectric Point: 4.3085

>AT111641 WP_050472155.1 NZ_CP032312:878984-879277 [Pannonibacter phragmitetus BB]
MALETFPFDAAEHLTDPVDQAELLNEALGSGDAAAIASALGIIARARGMTEVAREAGVTRVALYKSLSEEGDPRLTTLLG
VMRALGMKLSAEIMPAS

Download         Length: 294 bp

>AT111641 NZ_CP032312:878984-879277 [Pannonibacter phragmitetus BB]
ATGGCACTTGAAACCTTTCCGTTCGATGCCGCCGAGCACCTGACAGATCCAGTTGATCAGGCCGAGTTGCTGAACGAAGC
CTTGGGAAGCGGAGATGCCGCCGCTATCGCTTCCGCCCTCGGGATCATTGCCCGGGCACGCGGCATGACCGAAGTCGCCC
GCGAGGCCGGTGTAACCCGCGTCGCGCTTTACAAGTCCCTGAGCGAAGAGGGAGACCCCCGCCTGACAACCTTGCTGGGA
GTGATGCGGGCTTTGGGGATGAAGCTGTCTGCTGAGATTATGCCGGCTTCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References