Detailed information of TA system TA111640

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 826649..827310
• Replicon: chromosome
• Accession: NZ_CP032312
• Organism: Pannonibacter phragmitetus BB

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: P874_RS03940
• Protein ID: WP_094462450.1
• Coordinates: 826649..827086 (-)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: P874_RS03945
• Protein ID: WP_094462449.1
• Coordinates: 827083..827310 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P874_RS03900	821897..822400	-	504	WP_094462458.1	DUF2840 domain-containing protein	-
P874_RS03905	822397..823461	-	1065	WP_094462457.1	replication initiator protein A	-
P874_RS03910	823471..823752	-	282	WP_094462456.1	helix-turn-helix domain-containing protein	-
P874_RS03915	823930..824304	-	375	WP_094462455.1	DUF2285 domain-containing protein	-
P874_RS03920	824450..824701	-	252	WP_094462454.1	hypothetical protein	-
P874_RS03930	825194..825445	-	252	WP_094462452.1	hypothetical protein	-
P874_RS25115	825597..825764	-	168	WP_162936303.1	hypothetical protein	-
P874_RS03935	826162..826608	+	447	WP_094462451.1	hypothetical protein	-
P874_RS03940	826649..827086	-	438	WP_094462450.1	PIN domain-containing protein	Toxin
P874_RS03945	827083..827310	-	228	WP_094462449.1	CopG family transcriptional regulator	Antitoxin
P874_RS03950	827418..827819	-	402	WP_094462448.1	single-stranded DNA-binding protein	-
P874_RS03955	828734..829105	-	372	WP_094462447.1	hypothetical protein	-
P874_RS03960	829555..829971	-	417	WP_094462446.1	hypothetical protein	-
P874_RS03965	830139..831074	-	936	WP_094462514.1	DUF2493 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	757335..850021	92686

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-131)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 15437.65 Da
• Isoelectric Point: 5.4916

>T111640 WP_094462450.1 NZ_CP032312:c827086-826649 [Pannonibacter phragmitetus BB]
VTYLLDVNVLIALIDPAHVAHDAAHAWFGEAGALDWATCPLTENGVIRIVGNPKYPNSPGSPAVVAEIVSTLRNLPGHAF
WPDDLSLVGSEDVDTARLVNPAHVTDTYLLALAKSRQGQLATFDRKLPVAAVRKGAEALFLIPPT

Nucleotide

• Length: 438 bp

>T111640 NZ_CP032312:c827086-826649 [Pannonibacter phragmitetus BB]
GTGACCTACCTGCTCGACGTCAATGTGCTGATCGCCCTGATCGACCCGGCCCACGTGGCGCACGATGCCGCGCACGCTTG
GTTCGGCGAGGCCGGCGCGCTCGATTGGGCGACATGCCCGTTGACCGAGAACGGCGTCATACGCATCGTCGGCAACCCGA
AATATCCGAACTCGCCCGGCTCCCCCGCCGTGGTCGCCGAGATCGTTTCCACCTTGCGCAACCTGCCGGGCCACGCATTC
TGGCCCGATGATCTCAGCCTAGTCGGTTCCGAGGACGTCGACACCGCTCGTCTCGTCAATCCCGCCCACGTCACCGATAC
TTACCTGCTCGCTCTTGCGAAATCCCGGCAGGGGCAACTCGCGACGTTCGACCGGAAGCTTCCGGTCGCTGCCGTCCGGA
AGGGCGCGGAGGCGCTTTTTCTGATCCCGCCGACTTGA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8247.55 Da
• Isoelectric Point: 11.3495

>AT111640 WP_094462449.1 NZ_CP032312:c827310-827083 [Pannonibacter phragmitetus BB]
MRTTVTIDDDVLEAAKAMASQQNKPLGKVISDLARRSLARPRPREMRNGIPLLPGRAGARLVTLETVNALRDEQP

Nucleotide

• Length: 228 bp

>AT111640 NZ_CP032312:c827310-827083 [Pannonibacter phragmitetus BB]
ATGCGAACGACAGTGACCATTGATGACGACGTACTGGAGGCTGCCAAGGCGATGGCGTCTCAGCAGAACAAGCCGCTGGG
AAAGGTGATCTCCGACCTCGCGCGGCGTTCGCTTGCGCGCCCGCGGCCGCGCGAGATGCGCAATGGCATCCCTCTGCTTC
CCGGCCGCGCGGGCGCGCGCCTGGTGACGTTGGAAACCGTCAATGCGCTGCGTGACGAGCAGCCGTGA