Detailed information of TA system TA111639

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 413130..413920
• Replicon: chromosome
• Accession: NZ_CP032312
• Organism: Pannonibacter phragmitetus BB

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: P874_RS01930
• Protein ID: WP_094462830.1
• Coordinates: 413402..413920 (+)
• Length: 173 a.a.

Antitoxin (Protein)

• Gene name: tacA
• Uniprot ID: -
• Locus tag: P874_RS01925
• Protein ID: WP_094462829.1
• Coordinates: 413130..413405 (+)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P874_RS01900	408409..409176	+	768	WP_094462825.1	hypothetical protein	-
P874_RS01905	409173..411461	+	2289	WP_208999523.1	AAA family ATPase	-
P874_RS01910	411950..412429	+	480	WP_094462886.1	hypothetical protein	-
P874_RS01915	412426..412623	+	198	WP_094462827.1	hypothetical protein	-
P874_RS01920	412620..413075	+	456	WP_094462828.1	hypothetical protein	-
P874_RS01925	413130..413405	+	276	WP_094462829.1	DUF1778 domain-containing protein	Antitoxin
P874_RS01930	413402..413920	+	519	WP_094462830.1	GNAT family N-acetyltransferase	Toxin
P874_RS01935	414391..415716	+	1326	WP_094462831.1	site-specific DNA-methyltransferase	-
P874_RS01940	415713..415937	+	225	WP_094462832.1	hypothetical protein	-
P874_RS01945	415990..416535	-	546	WP_094462833.1	DUF3489 domain-containing protein	-
P874_RS01950	416634..416858	-	225	WP_094462834.1	hypothetical protein	-
P874_RS01955	416973..417533	+	561	WP_094462835.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (49-150)

Antitoxin

• Vibrio phage ICP1, Orf50 (10-86)

Sequences

Toxin

Protein

• Length: 173 a.a.
• Molecular weight: 18774.41 Da
• Isoelectric Point: 7.0625

>T111639 WP_094462830.1 NZ_CP032312:413402-413920 [Pannonibacter phragmitetus BB]
VTAENQAFSAVKKLDASHDVDAFDSGKEPLDRFLQRHALINQKAGSAQTYVVCRGEQRVVGYYSLAVGAVEHADAPGRVG
KGLARHPIPVMLLARLAIDRSEQGKGLGKALLKDALLRTAQAADIAGIRALLVHAKDDEARAWYEQFDFDPSPTDPYHLF
LLMKDLRGLLGE

Nucleotide

• Length: 519 bp

>T111639 NZ_CP032312:413402-413920 [Pannonibacter phragmitetus BB]
GTGACGGCGGAGAACCAAGCGTTCTCTGCCGTCAAAAAGCTCGATGCCTCCCACGACGTCGACGCGTTTGATTCCGGCAA
GGAACCTCTCGACCGTTTTCTGCAACGCCACGCTCTGATCAACCAGAAAGCGGGCAGCGCCCAGACCTATGTCGTCTGCC
GTGGCGAGCAGCGTGTCGTGGGCTACTACAGCCTCGCGGTCGGTGCCGTCGAACATGCCGACGCCCCGGGTCGCGTCGGC
AAAGGGCTTGCCCGCCATCCGATCCCGGTGATGCTCCTCGCCCGTCTTGCCATCGACCGATCCGAGCAGGGCAAGGGGCT
CGGCAAGGCCTTGCTCAAGGATGCACTGTTGCGCACGGCTCAAGCTGCCGACATTGCAGGTATTCGAGCGCTGCTCGTGC
ATGCCAAGGACGATGAAGCACGCGCTTGGTACGAGCAATTCGATTTCGACCCGAGTCCGACCGACCCCTATCATCTCTTC
CTGCTGATGAAAGATCTGCGGGGGCTCCTCGGCGAATGA

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 10359.96 Da
• Isoelectric Point: 7.2060

>AT111639 WP_094462829.1 NZ_CP032312:413130-413405 [Pannonibacter phragmitetus BB]
MPVAEAKSERIEVRTTPTMKALLQRAATFSHKNVTEFLLEAGIHAAEEALVDRRMFRLDDAQWQAFQDVLDRPVQSKPRL
AKLLAEKSVLE

Nucleotide

• Length: 276 bp

>AT111639 NZ_CP032312:413130-413405 [Pannonibacter phragmitetus BB]
ATGCCCGTAGCCGAAGCCAAGTCCGAACGTATCGAAGTGCGCACCACGCCGACCATGAAGGCGCTGCTGCAGCGTGCAGC
CACGTTTTCGCACAAGAACGTGACGGAGTTCCTGCTCGAGGCGGGCATTCATGCCGCCGAGGAAGCGCTCGTCGATCGGC
GTATGTTCCGGCTGGATGATGCCCAGTGGCAAGCTTTTCAGGATGTTCTCGACCGTCCCGTCCAGAGCAAGCCGCGCCTC
GCCAAACTGCTTGCCGAGAAGAGCGTGCTTGAGTGA