Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5211802..5212442 Replicon chromosome
Accession NZ_CP032311
Organism Pseudomonas sp. DG56-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D3Z90_RS23935 Protein ID WP_136478351.1
Coordinates 5212032..5212442 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D3Z90_RS23930 Protein ID WP_136478350.1
Coordinates 5211802..5212032 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3Z90_RS23910 5207258..5208595 - 1338 WP_136478346.1 precorrin-3B synthase -
D3Z90_RS23915 5208713..5209924 + 1212 WP_136478347.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
D3Z90_RS23920 5209917..5211014 + 1098 WP_136478348.1 cobalt-precorrin-5B (C(1))-methyltransferase -
D3Z90_RS23925 5211011..5211742 + 732 WP_136478349.1 cobalt-precorrin-6A reductase -
D3Z90_RS23930 5211802..5212032 + 231 WP_136478350.1 antitoxin Antitoxin
D3Z90_RS23935 5212032..5212442 + 411 WP_136478351.1 tRNA(fMet)-specific endonuclease VapC Toxin
D3Z90_RS23940 5212545..5212982 + 438 WP_136478352.1 NfeD family protein -
D3Z90_RS23945 5213006..5213863 + 858 WP_136478353.1 SPFH/Band 7/PHB domain protein -
D3Z90_RS23950 5213984..5214370 + 387 WP_136478354.1 DUF2946 domain-containing protein -
D3Z90_RS23955 5214417..5214887 + 471 WP_136478355.1 copper chaperone PCu(A)C -
D3Z90_RS23960 5214907..5215311 + 405 WP_136478356.1 DUF2946 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15152.40 Da        Isoelectric Point: 7.3220

>T111638 WP_136478351.1 NZ_CP032311:5212032-5212442 [Pseudomonas sp. DG56-2]
MLKYMLDTNICIFTLKNRPQEVREAFNRHHGQLCISTITLMELFYGAEKSAAPERNLSVVEGFAARLEVLSYDNLAAAHS
GQLRAELAKAGTPVGPYDQMIAGHARSLGLILVSNNLREFQRVPGLRVEDWLNPAN

Download         Length: 411 bp

>T111638 NZ_CP032311:5212032-5212442 [Pseudomonas sp. DG56-2]
ATGCTCAAGTACATGCTCGACACCAACATCTGCATATTCACCCTTAAGAACCGGCCTCAGGAAGTCCGGGAAGCGTTCAA
CCGCCATCACGGTCAGCTGTGCATCAGCACAATTACACTTATGGAATTGTTTTACGGTGCCGAAAAATCTGCCGCCCCTG
AGCGTAATTTATCCGTGGTCGAAGGCTTTGCCGCACGCCTTGAAGTTCTCAGTTACGACAATCTTGCAGCGGCCCACAGT
GGTCAGCTACGCGCGGAATTGGCCAAGGCTGGAACACCCGTCGGCCCCTACGATCAAATGATCGCAGGACATGCCCGTTC
GCTGGGCCTTATTTTGGTAAGCAATAATCTACGCGAATTTCAGCGAGTTCCGGGATTGCGAGTGGAGGACTGGCTGAACC
CAGCCAACTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8397.42 Da        Isoelectric Point: 4.5203

>AT111638 WP_136478350.1 NZ_CP032311:5211802-5212032 [Pseudomonas sp. DG56-2]
MDQGAVFKSNRSQAIRLPKSVALPEEITRVDVVAIGRTRIITPAGEAWDSWFEGECVSADFMASRAQPADQEREGF

Download         Length: 231 bp

>AT111638 NZ_CP032311:5211802-5212032 [Pseudomonas sp. DG56-2]
ATGGACCAAGGTGCCGTCTTCAAAAGCAACCGCAGTCAGGCCATCCGCTTGCCAAAGTCCGTCGCACTTCCGGAAGAAAT
TACCCGCGTGGATGTGGTCGCCATCGGCCGAACGCGGATCATTACACCTGCAGGCGAAGCTTGGGATAGCTGGTTCGAGG
GCGAATGCGTCAGCGCGGATTTCATGGCTTCACGGGCGCAACCCGCTGATCAGGAGCGCGAAGGGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References