Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3627609..3628226 Replicon chromosome
Accession NZ_CP032296
Organism Rahnella aquatilis strain ZF7

Toxin (Protein)


Gene name Hha Uniprot ID H8NYI7
Locus tag D3Z09_RS16880 Protein ID WP_013576617.1
Coordinates 3628023..3628226 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID H8NYI6
Locus tag D3Z09_RS16875 Protein ID WP_013576616.1
Coordinates 3627609..3627977 (+) Length 123 a.a.

Genomic Context

D3Z09_RS16845D3Z09_RS16850D3Z09_RS16870D3Z09_RS16875D3Z09_RS16880D3Z09_RS16890D3Z09_RS16895D3Z09_RS16855D3Z09_RS16860D3Z09_RS16865D3Z09_RS16885
Location: 3623599..3623853 (255 bp)
Type: Others
Protein ID: WP_013576610.1
Location: 3623874..3624014 (141 bp)
Type: Others
Protein ID: WP_013576611.1
Location: 3627026..3627379 (354 bp)
Type: Others
Protein ID: WP_013576615.1
Location: 3627609..3627977 (369 bp)
Type: Antitoxin
Protein ID: WP_013576616.1
Location: 3628023..3628226 (204 bp)
Type: Toxin
Protein ID: WP_013576617.1
Location: 3629398..3631185 (1788 bp)
Type: Others
Protein ID: WP_013576619.1
Location: 3631262..3632611 (1350 bp)
Type: Others
Protein ID: WP_119261884.1
Location: 3624139..3625017 (879 bp)
Type: Others
Protein ID: WP_013576612.1
Location: 3625061..3625918 (858 bp)
Type: Others
Protein ID: WP_013576613.1
Location: 3625915..3626643 (729 bp)
Type: Others
Protein ID: WP_173362112.1
Location: 3628302..3629258 (957 bp)
Type: Others
Protein ID: WP_013576618.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D3Z09_RS168453623599..3623853+255WP_013576610.1type B 50S ribosomal protein L31-
D3Z09_RS168503623874..3624014+141WP_013576611.1type B 50S ribosomal protein L36-
D3Z09_RS168553624139..3625017-879WP_013576612.1metal ABC transporter substrate-binding protein-
D3Z09_RS168603625061..3625918-858WP_013576613.1metal ABC transporter permease-
D3Z09_RS168653625915..3626643-729WP_173362112.1ABC transporter ATP-binding protein-
D3Z09_RS168703627026..3627379+354WP_013576615.1hypothetical protein-
D3Z09_RS168753627609..3627977+369WP_013576616.1Hha toxicity modulator TomBAntitoxin
D3Z09_RS168803628023..3628226+204WP_013576617.1hemolysin expression modulator HhaToxin
D3Z09_RS168853628302..3629258-957WP_013576618.1LysR family transcriptional regulator-
D3Z09_RS168903629398..3631185+1788WP_013576619.1adenine deaminase-
D3Z09_RS168953631262..3632611+1350WP_119261884.1NCS2 family permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8114.45 Da        Isoelectric Point: 6.9764

>T111608 WP_013576617.1 NZ_CP032296:3628023-3628226 [Rahnella aquatilis]
MNKIDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPVSVWKFVR

Download         Length: 204 bp

>T111608 NZ_CP032296:3628023-3628226 [Rahnella aquatilis]
ATGAACAAAATCGACTATTTGATGCGTTTACGAAAATGCACCACTATCGATACACTTGAACGTGTTATTGAAAAAAATAA
GTACGAACTTTCCGACGACGAGCTGGAATTGTTTTACTCGGCAGCTGACCATCGTTTAGCGGAGCTAACGATGAACAAGT
TGTACGATAAAATCCCGGTATCAGTCTGGAAATTTGTACGCTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14391.15 Da        Isoelectric Point: 4.7281

>AT111608 WP_013576616.1 NZ_CP032296:3627609-3627977 [Rahnella aquatilis]
MDEYSPKRHDIAQLRYLNEMLYDEGIATLGDSHHGWVNDPTSAVNLQLNELIEHIASFVMSFKIKYPDDNHLSDLVEEYL
DDTYTLFSNYGINDSDLRQWQKTKKRLFRMFSGDYICTLMKT

Download         Length: 369 bp

>AT111608 NZ_CP032296:3627609-3627977 [Rahnella aquatilis]
ATGGATGAGTACTCGCCTAAGCGGCACGATATCGCTCAGTTACGCTACCTGAATGAAATGCTGTATGATGAAGGGATTGC
GACACTGGGTGACAGTCATCATGGTTGGGTTAACGATCCGACTTCGGCTGTTAACTTGCAGCTCAATGAACTGATTGAGC
ACATTGCATCCTTTGTGATGAGTTTTAAAATTAAGTATCCAGACGATAACCATTTAAGTGATCTGGTTGAAGAGTATCTG
GATGATACCTACACGCTGTTCAGTAATTATGGAATTAACGATTCTGATTTACGCCAATGGCAAAAGACCAAGAAGCGGTT
ATTCAGAATGTTCTCAGGGGACTACATCTGTACCCTAATGAAGACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBH8NYI7

Antitoxin

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Source
ID
Structure
AlphaFold DBH8NYI6

References