Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 621058..621780 Replicon chromosome
Accession NZ_CP032296
Organism Rahnella aquatilis strain ZF7

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag D3Z09_RS02865 Protein ID WP_119261205.1
Coordinates 621460..621780 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag D3Z09_RS02860 Protein ID WP_119261204.1
Coordinates 621058..621393 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3Z09_RS02840 616180..616578 + 399 WP_119261201.1 hypothetical protein -
D3Z09_RS02845 616963..618021 - 1059 WP_119262217.1 HNH endonuclease -
D3Z09_RS02850 618199..620193 - 1995 WP_119261202.1 NERD domain-containing protein -
D3Z09_RS02855 620565..621044 + 480 WP_119261203.1 DNA repair protein RadC -
D3Z09_RS02860 621058..621393 + 336 WP_119261204.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
D3Z09_RS02865 621460..621780 + 321 WP_119261205.1 TA system toxin CbtA family protein Toxin
D3Z09_RS02870 621894..622727 + 834 WP_119261206.1 DUF4942 domain-containing protein -
D3Z09_RS02875 622991..624760 - 1770 WP_119261207.1 hypothetical protein -
D3Z09_RS02880 624762..625790 - 1029 WP_119261208.1 tyrosine-type recombinase/integrase -
D3Z09_RS02885 625793..626374 - 582 WP_119261209.1 phage repressor protein CI -
D3Z09_RS02890 626515..626736 + 222 WP_112152073.1 regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11943.67 Da        Isoelectric Point: 4.7440

>T111595 WP_119261205.1 NZ_CP032296:621460-621780 [Rahnella aquatilis]
MQISTVPATVPVSSRLSPVMVWQLLLTYLLENHYGLTLNDTPFHDDAAIEEHIDAGITLADAVNFLVERYELVRIDRKGF
SWQEQAPFLTATDILRAKRATGLMNT

Download         Length: 321 bp

>T111595 NZ_CP032296:621460-621780 [Rahnella aquatilis]
ATGCAAATTTCAACTGTACCGGCCACGGTGCCGGTTTCGTCACGCCTGTCGCCCGTAATGGTGTGGCAGCTGCTGTTAAC
GTATCTGCTGGAGAACCACTACGGCCTGACTCTCAACGACACGCCATTTCATGACGACGCGGCCATTGAGGAGCATATTG
ACGCAGGAATCACGCTTGCCGATGCGGTTAATTTTCTGGTGGAACGTTATGAACTGGTACGCATCGACCGCAAAGGGTTT
AGCTGGCAGGAACAGGCTCCGTTCCTTACCGCTACCGATATTCTCAGGGCAAAGCGTGCTACCGGGCTGATGAATACGTA
A

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12556.37 Da        Isoelectric Point: 6.3149

>AT111595 WP_119261204.1 NZ_CP032296:621058-621393 [Rahnella aquatilis]
MNKDATQTWGLKRDITPCFGARLVQEGHRLHFLADRAGFNVSFSEMQARDLEEAFPHFVAHMELMLLSGELNPWCAHCIT
LYRNGLTCEADTLGSYGYVYIAIYPSNLVKA

Download         Length: 336 bp

>AT111595 NZ_CP032296:621058-621393 [Rahnella aquatilis]
ATGAATAAAGACGCTACCCAGACATGGGGTCTTAAACGAGACATCACTCCCTGCTTCGGAGCCCGACTGGTGCAGGAAGG
TCATCGTCTGCATTTTCTGGCGGACCGAGCAGGATTCAACGTTTCGTTCAGCGAGATGCAGGCCCGAGATCTGGAGGAAG
CCTTTCCGCATTTTGTCGCGCATATGGAATTGATGCTGCTCTCCGGTGAGTTGAATCCTTGGTGCGCGCACTGCATCACG
CTGTACCGTAACGGGTTAACCTGTGAAGCCGACACGCTGGGTAGTTATGGGTATGTATATATCGCAATTTATCCCTCAAA
TCTGGTTAAAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References