Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 432107..432756 Replicon chromosome
Accession NZ_CP032286
Organism Acinetobacter sp. WCHA55

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag CDG62_RS04845 Protein ID WP_087527392.1
Coordinates 432370..432756 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag CDG62_RS04840 Protein ID WP_087527391.1
Coordinates 432107..432364 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDG62_RS04820 427727..428092 + 366 WP_004691290.1 50S ribosomal protein L17 -
CDG62_RS04825 428287..429777 + 1491 WP_087527389.1 NAD(P)/FAD-dependent oxidoreductase -
CDG62_RS04830 429916..430706 + 791 Protein_375 alpha/beta hydrolase -
CDG62_RS04835 430742..431914 - 1173 WP_087527390.1 acyl-CoA dehydrogenase family protein -
CDG62_RS04840 432107..432364 + 258 WP_087527391.1 succinate dehydrogenase assembly factor 2 Antitoxin
CDG62_RS04845 432370..432756 + 387 WP_087527392.1 hypothetical protein Toxin
CDG62_RS04850 433277..434314 + 1038 WP_087527393.1 hypothetical protein -
CDG62_RS04855 434385..434957 + 573 WP_087527394.1 rhombosortase -
CDG62_RS04860 435139..437421 + 2283 WP_087527395.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(6-127)

Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 15368.30 Da        Isoelectric Point: 10.3370

>T111590 WP_087527392.1 NZ_CP032286:432370-432756 [Acinetobacter sp. WCHA55]
MEHRYFQLKPSRVAYVFQLSIYAVLMFVLYQLLPLGVWLIALVAGFVLYLFFLRGPQHFQLQHLDGRDWSLSHQKQTNVQ
RVQISHIVDHRAYIVIYFQHFRAKPMLVWCDQLPIPQWKALKILTKMQ

Download         Length: 387 bp

>T111590 NZ_CP032286:432370-432756 [Acinetobacter sp. WCHA55]
ATGGAACATCGTTATTTTCAACTTAAACCCAGTCGTGTGGCTTATGTGTTTCAGTTGTCGATTTATGCCGTTCTAATGTT
TGTCCTGTATCAGCTACTTCCTTTAGGAGTGTGGCTGATCGCTTTAGTTGCTGGCTTTGTGCTGTATTTGTTTTTTCTAC
GTGGGCCGCAACATTTTCAGCTTCAGCATTTAGATGGTCGTGATTGGTCTTTGTCACATCAGAAACAAACCAATGTACAG
CGGGTACAGATCAGTCATATTGTGGATCATCGCGCTTATATTGTGATTTATTTTCAACACTTTAGAGCAAAACCGATGTT
GGTTTGGTGTGATCAGCTACCAATCCCACAATGGAAAGCCCTGAAAATACTCACCAAAATGCAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10152.62 Da        Isoelectric Point: 4.7091

>AT111590 WP_087527391.1 NZ_CP032286:432107-432364 [Acinetobacter sp. WCHA55]
MTEEMSLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADPAEKAMFAALVEQEDPDLLDWFMEVSEPPHSEMKTLIQKLK
HYVHG

Download         Length: 258 bp

>AT111590 NZ_CP032286:432107-432364 [Acinetobacter sp. WCHA55]
ATGACTGAAGAAATGAGCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAAGAAATTGATGTGTATTT
TGACCCTTATGTGAAGAATTATTATCTTCAGGCGGATCCTGCGGAAAAGGCCATGTTTGCTGCTTTGGTTGAACAGGAAG
ATCCAGATTTGCTGGATTGGTTTATGGAAGTCTCTGAGCCACCGCATTCTGAAATGAAAACTTTGATTCAAAAATTAAAA
CACTATGTACACGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References