Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 4952..5465 Replicon plasmid p3_010055
Accession NZ_CP032282
Organism Acinetobacter sp. WCHA55

Toxin (Protein)


Gene name yoeB Uniprot ID N8YGB2
Locus tag CDG62_RS00565 Protein ID WP_000184943.1
Coordinates 4952..5215 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID N8ZW56
Locus tag CDG62_RS00570 Protein ID WP_000557944.1
Coordinates 5202..5465 (-) Length 88 a.a.

Genomic Context

CDG62_RS00560CDG62_RS00575CDG62_RS00585CDG62_RS00540CDG62_RS00545CDG62_RS00555CDG62_RS00565CDG62_RS00570
Location: 4588..4890 (303 bp)
Type: Others
Protein ID: WP_000110201.1
Location: 5862..7430 (1569 bp)
Type: Others
Protein ID: WP_087528895.1
Location: 7611..8936 (1326 bp)
Type: Others
Protein ID: WP_020899627.1
Location: 787..1074 (288 bp)
Type: Others
Protein ID: WP_004870774.1
Location: 1071..2012 (942 bp)
Type: Others
Protein ID: WP_020846814.1
Location: 2724..4376 (1653 bp)
Type: Others
Protein ID: WP_004870770.1
Location: 4952..5215 (264 bp)
Type: Toxin
Protein ID: WP_000184943.1
Location: 5202..5465 (264 bp)
Type: Antitoxin
Protein ID: WP_000557944.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CDG62_RS00540787..1074-288WP_004870774.1hypothetical protein-
CDG62_RS005451071..2012-942WP_020846814.1replication initiation protein-
CDG62_RS005552724..4376-1653WP_004870770.1MobA/MobL family protein-
CDG62_RS005604588..4890+303WP_000110201.1hypothetical protein-
CDG62_RS005654952..5215-264WP_000184943.1Txe/YoeB family addiction module toxinToxin
CDG62_RS005705202..5465-264WP_000557944.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
CDG62_RS005755862..7430+1569WP_087528895.1ATP-binding cassette domain-containing protein-
CDG62_RS005857611..8936+1326WP_020899627.1ISNCY family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..1483814838
-flankIS/Tn--20..685665
-flankIS/Tn--7599..89361337


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10649.09 Da        Isoelectric Point: 8.4866

>T111587 WP_000184943.1 NZ_CP032282:c5215-4952 [Acinetobacter sp. WCHA55]
MTNRNVEWTDNAWDEYIYWQTQDKKILKRINTLIKECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

>T111587 NZ_CP032282:c5215-4952 [Acinetobacter sp. WCHA55]
ATGACGAATCGTAACGTCGAATGGACTGATAATGCCTGGGATGAATATATCTATTGGCAGACACAGGATAAAAAGATACT
TAAGCGTATTAATACCTTAATCAAAGAATGTCAGCGAACACCTTTTGAAGGAACAGGAAAACCAGAACCTTTAAAAGCTA
ATCTTTCAGGATTTTGGAGTCGTAGGATTGATGAAAAGCATAGATTAGTTTATGAAGTGACAGATGAACGAATCTCTATA
ATTCAATGTCGATTCCATTACTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9834.99 Da        Isoelectric Point: 5.0829

>AT111587 WP_000557944.1 NZ_CP032282:c5465-5202 [Acinetobacter sp. WCHA55]
MHVFTYTDARNNLKSVLDKVIDDVDVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNASRLNESIAQLRAGKTKHRE
LIEDDES

Download         Length: 264 bp

>AT111587 NZ_CP032282:c5465-5202 [Acinetobacter sp. WCHA55]
ATGCATGTATTTACATATACGGACGCACGTAACAATTTAAAATCTGTTTTAGATAAAGTAATTGATGATGTAGACGTTGC
TTTTATTACAAGAAAAGAAGGTGGCCATGCTGTAGTAATGGGACAAGATCATTATGATAGCTTAATGGAAACGTTATATC
TCCTTTCATCTCCAAATAATGCAAGTCGTTTAAATGAATCAATTGCTCAATTACGTGCAGGGAAAACAAAACACAGAGAG
TTGATTGAGGATGACGAATCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A6C0XPS2

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A6C0XPU2

References