Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1889858..1890003 Replicon chromosome
Accession NZ_CP032222
Organism Klebsiella pneumoniae strain AR_0046

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1889865..1889967 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1889858..1890003 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM425_RS09420 1885389..1886822 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM425_RS09425 1886938..1887177 + 240 WP_002911393.1 YebV family protein -
AM425_RS09430 1887275..1887466 + 192 WP_002911395.1 YebW family protein -
AM425_RS09435 1887463..1888116 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
AM425_RS09440 1888273..1889241 + 969 WP_014907334.1 VirK/YbjX family protein -
AM425_RS29645 1889346..1889489 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 1889858..1890003 + 146 - - Antitoxin
- 1889865..1889967 - 103 - - Toxin
AM425_RS09450 1890126..1890464 - 339 WP_002911404.1 YebY family protein -
AM425_RS09455 1890481..1891350 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
AM425_RS09460 1891354..1891728 - 375 WP_060577972.1 CopC domain-containing protein YobA -
AM425_RS09465 1891841..1892071 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM425_RS09470 1892150..1892809 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM425_RS09475 1892813..1894873 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T111403 NZ_CP032222:c1889967-1889865 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT111403 NZ_CP032222:1889858-1890003 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References