Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3805805..3805950 Replicon chromosome
Accession NZ_CP032200
Organism Klebsiella pneumoniae strain AR_0097

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3805841..3805943 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3805805..3805950 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM476_RS21410 3800935..3802995 + 2061 WP_047694778.1 oligopeptidase B -
AM476_RS21415 3802999..3803658 - 660 WP_002911407.1 exodeoxyribonuclease X -
AM476_RS21420 3803737..3803967 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM476_RS21425 3804080..3804454 + 375 WP_023285314.1 CopC domain-containing protein YobA -
AM476_RS21430 3804458..3805327 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
AM476_RS21435 3805344..3805682 + 339 WP_002911404.1 YebY family protein -
- 3805805..3805950 - 146 - - Antitoxin
- 3805841..3805943 + 103 - - Toxin
AM476_RS30010 3806318..3806461 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM476_RS21445 3806566..3807534 - 969 WP_004151446.1 VirK/YbjX family protein -
AM476_RS21450 3807691..3808344 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
AM476_RS21455 3808341..3808532 - 192 WP_002911395.1 YebW family protein -
AM476_RS21460 3808630..3808869 - 240 WP_002911393.1 YebV family protein -
AM476_RS21465 3808985..3810418 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T111306 NZ_CP032200:3805841-3805943 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT111306 NZ_CP032200:c3805950-3805805 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References