Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2868833..2868978 Replicon chromosome
Accession NZ_CP032185
Organism Klebsiella pneumoniae strain AR_0075

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2868840..2868942 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2868833..2868978 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM454_RS14620 2864364..2865797 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM454_RS14625 2865913..2866152 + 240 WP_002911393.1 YebV family protein -
AM454_RS14630 2866250..2866441 + 192 WP_002911395.1 YebW family protein -
AM454_RS14635 2866438..2867091 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
AM454_RS14640 2867248..2868216 + 969 WP_004151446.1 VirK/YbjX family protein -
AM454_RS31335 2868321..2868464 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2868833..2868978 + 146 - - Antitoxin
- 2868840..2868942 - 103 - - Toxin
AM454_RS14650 2869101..2869439 - 339 WP_009307539.1 YebY family protein -
AM454_RS14655 2869456..2870325 - 870 WP_009307538.1 copper homeostasis membrane protein CopD -
AM454_RS14660 2870329..2870703 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AM454_RS14665 2870816..2871046 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM454_RS14670 2871125..2871784 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM454_RS14675 2871788..2873848 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T111275 NZ_CP032185:c2868942-2868840 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT111275 NZ_CP032185:2868833-2868978 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References