Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1565442..1565587 Replicon chromosome
Accession NZ_CP032167
Organism Klebsiella pneumoniae strain AR_0076

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1565478..1565580 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1565442..1565587 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM455_RS08125 1560572..1562632 + 2061 WP_119177255.1 oligopeptidase B -
AM455_RS08130 1562636..1563295 - 660 WP_002911407.1 exodeoxyribonuclease X -
AM455_RS08135 1563374..1563604 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM455_RS08140 1563717..1564091 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AM455_RS08145 1564095..1564964 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
AM455_RS08150 1564981..1565319 + 339 WP_002911404.1 YebY family protein -
- 1565442..1565587 - 146 - - Antitoxin
- 1565478..1565580 + 103 - - Toxin
AM455_RS29060 1565956..1566099 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM455_RS08160 1566204..1567172 - 969 WP_004151446.1 VirK/YbjX family protein -
AM455_RS08165 1567329..1567982 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
AM455_RS08170 1567979..1568170 - 192 WP_002911395.1 YebW family protein -
AM455_RS08175 1568268..1568507 - 240 WP_002911393.1 YebV family protein -
AM455_RS08180 1568623..1570056 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1491850..1572813 80963


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T111212 NZ_CP032167:1565478-1565580 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT111212 NZ_CP032167:c1565587-1565442 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References