Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2023316..2023461 Replicon chromosome
Accession NZ_CP032163
Organism Klebsiella pneumoniae strain XJ-K1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2023352..2023454 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2023316..2023461 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3H40_RS10055 2018446..2020506 + 2061 WP_004151449.1 oligopeptidase B -
D3H40_RS10060 2020510..2021169 - 660 WP_002911407.1 exodeoxyribonuclease X -
D3H40_RS10065 2021248..2021478 - 231 WP_002911406.1 DNA polymerase III subunit theta -
D3H40_RS10070 2021591..2021965 + 375 WP_004151448.1 CopC domain-containing protein YobA -
D3H40_RS10075 2021969..2022838 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
D3H40_RS10080 2022855..2023193 + 339 WP_002911404.1 YebY family protein -
- 2023316..2023461 - 146 - - Antitoxin
- 2023352..2023454 + 103 - - Toxin
D3H40_RS30255 2023829..2023972 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
D3H40_RS10090 2024077..2025045 - 969 WP_004151446.1 VirK/YbjX family protein -
D3H40_RS10095 2025202..2025855 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
D3H40_RS10100 2025852..2026043 - 192 WP_002911395.1 YebW family protein -
D3H40_RS10105 2026141..2026380 - 240 WP_002911393.1 YebV family protein -
D3H40_RS10110 2026496..2027929 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T111184 NZ_CP032163:2023352-2023454 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT111184 NZ_CP032163:c2023461-2023316 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References