Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1701742..1702871 Replicon chromosome
Accession NZ_CP032143
Organism Acinetobacter sp. WCHAc010052

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag CDG61_RS08520 Protein ID WP_087550085.1
Coordinates 1702110..1702871 (+) Length 254 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag CDG61_RS08515 Protein ID WP_087550086.1
Coordinates 1701742..1702113 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDG61_RS08495 1697606..1698844 + 1239 WP_087550090.1 acyl-CoA dehydrogenase family protein -
CDG61_RS08500 1698954..1700075 + 1122 WP_087550089.1 phosphotransferase family protein -
CDG61_RS08505 1700072..1700770 + 699 WP_087550088.1 phosphoglycerate mutase family protein -
CDG61_RS08510 1700784..1701527 + 744 WP_087550087.1 SDR family oxidoreductase -
CDG61_RS08515 1701742..1702113 + 372 WP_087550086.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
CDG61_RS08520 1702110..1702871 + 762 WP_087550085.1 RES family NAD+ phosphorylase Toxin
CDG61_RS08525 1702887..1703597 + 711 WP_087550084.1 SGNH/GDSL hydrolase family protein -
CDG61_RS08530 1703947..1704357 + 411 WP_087550083.1 hypothetical protein -
CDG61_RS08535 1704613..1705140 + 528 WP_087550082.1 hypothetical protein -
CDG61_RS08540 1705243..1705833 + 591 WP_087550081.1 uracil-DNA glycosylase family protein -
CDG61_RS08545 1705903..1706766 - 864 WP_087550351.1 DMT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(65-201)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(73-121)


Sequences

Toxin        


Download         Length: 254 a.a.        Molecular weight: 28797.86 Da        Isoelectric Point: 7.0826

>T111127 WP_087550085.1 NZ_CP032143:1702110-1702871 [Acinetobacter sp. WCHAc010052]
MTAVLDLWQECHGQQQIKPIAGTLYRLVESQEQIATRQLVDTLEEQALLEDLLESVKPPYPADMEKLHYLLKSPFRYPPL
KWGSRYGRTFEPSIFYGGCSVAVTLAESAYYRFVFLKSMQGTSVKSMIRSEHTLFSVGYKCKKGLRLQDVPFNRHLELLA
HPKNYAYSQALGTSMREAGIEAFEYPSARDENHATCVGLFSAQYFTGNSPKTREQWFCDVSANDVVFKAVESATIVRFEL
SQFLQHGQFPLPA

Download         Length: 762 bp

>T111127 NZ_CP032143:1702110-1702871 [Acinetobacter sp. WCHAc010052]
ATGACTGCTGTACTTGATCTATGGCAGGAATGTCATGGACAGCAACAGATCAAGCCTATAGCAGGTACGCTGTACAGACT
TGTAGAAAGTCAGGAACAGATCGCAACCCGACAGCTTGTCGACACACTGGAAGAACAGGCTTTACTGGAGGACTTACTCG
AATCAGTGAAGCCACCCTATCCAGCAGATATGGAAAAACTTCATTACCTGCTGAAATCACCATTCAGATACCCACCTTTA
AAATGGGGTTCACGCTATGGAAGGACTTTTGAGCCGAGTATTTTTTATGGTGGATGCAGCGTAGCAGTTACTTTGGCAGA
ATCTGCATACTATCGTTTTGTATTCCTGAAATCCATGCAGGGCACATCTGTAAAAAGTATGATACGCTCAGAACATACTT
TATTTTCAGTGGGTTATAAGTGTAAAAAAGGTCTTCGTTTACAGGATGTACCTTTTAACAGACATCTGGAACTGTTGGCT
CACCCTAAAAATTATGCTTATTCTCAGGCTTTAGGTACATCCATGCGTGAAGCGGGTATTGAAGCGTTTGAGTATCCATC
TGCACGGGATGAAAATCATGCAACCTGTGTTGGATTGTTCAGTGCTCAATATTTTACAGGAAACAGCCCTAAGACCAGAG
AACAGTGGTTCTGTGATGTTTCTGCAAATGATGTCGTATTTAAAGCGGTAGAAAGTGCAACCATCGTCCGTTTTGAACTG
TCTCAGTTTTTGCAGCACGGACAGTTTCCTTTACCTGCCTGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13365.71 Da        Isoelectric Point: 10.0447

>AT111127 WP_087550086.1 NZ_CP032143:1701742-1702113 [Acinetobacter sp. WCHAc010052]
MSALLKQPIEKNVVLAKAVLNAAEQLELKQTQLAAILGVHRTAISRLKSNPELDPSSKQGELALLLIRIYRALYALAGGD
LDWMRHFINTPNLVTGGVPVQQIESITGLVSVVNFLDALRGKV

Download         Length: 372 bp

>AT111127 NZ_CP032143:1701742-1702113 [Acinetobacter sp. WCHAc010052]
ATGAGTGCATTACTGAAACAACCTATAGAAAAAAATGTCGTTCTGGCAAAAGCTGTACTGAATGCAGCAGAACAGCTGGA
ACTGAAACAGACACAGCTGGCTGCCATTTTAGGTGTCCATCGTACTGCCATCAGTCGTTTAAAAAGCAATCCTGAGCTTG
ATCCATCATCCAAGCAGGGTGAACTGGCACTGTTGCTGATTCGTATTTACCGTGCGCTTTATGCTCTGGCGGGTGGAGAT
CTGGATTGGATGCGTCATTTTATCAATACACCGAACCTGGTCACAGGTGGTGTACCTGTACAGCAGATTGAAAGCATCAC
AGGTCTGGTCAGCGTGGTCAATTTCCTTGATGCGCTGCGGGGTAAAGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References