Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2889953..2890602 Replicon chromosome
Accession NZ_CP032134
Organism Acinetobacter chinensis strain WCHAc010005

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CDG60_RS14645 Protein ID WP_087513980.1
Coordinates 2889953..2890372 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CDG60_RS14650 Protein ID WP_087513979.1
Coordinates 2890372..2890602 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDG60_RS14615 2885356..2886471 + 1116 WP_087513984.1 glycine oxidase ThiO -
CDG60_RS14620 2886457..2887362 - 906 WP_087513983.1 TIGR01777 family oxidoreductase -
CDG60_RS14625 2887548..2887994 - 447 WP_087513982.1 ABZJ_00895 family protein -
CDG60_RS14630 2888447..2889028 - 582 WP_087513994.1 DUF4126 domain-containing protein -
CDG60_RS14635 2889157..2889291 - 135 WP_111858212.1 hypothetical protein -
CDG60_RS14640 2889521..2889883 - 363 WP_087513981.1 hypothetical protein -
CDG60_RS14645 2889953..2890372 - 420 WP_087513980.1 type II toxin-antitoxin system VapC family toxin Toxin
CDG60_RS14650 2890372..2890602 - 231 WP_087513979.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CDG60_RS14655 2890726..2891382 - 657 WP_087513978.1 hypothetical protein -
CDG60_RS14660 2891476..2894094 - 2619 WP_087513977.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
CDG60_RS14665 2894395..2894811 + 417 WP_087513976.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-127)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16054.55 Da        Isoelectric Point: 6.6438

>T111123 WP_087513980.1 NZ_CP032134:c2890372-2889953 [Acinetobacter chinensis]
MPTQYLLDTNICISITKHQPEIVRQHFEKHLPNRNILMSVITLGELRFGAEKSQNKEKALKVIDELTSIIPVVELDETVA
EHYAQIRKDLTLKGQIIGNNDLWLAAHARANDWVMVTNNEKEFLRVDQLKIENWVTKAI

Download         Length: 420 bp

>T111123 NZ_CP032134:c2890372-2889953 [Acinetobacter chinensis]
ATGCCGACACAATACTTATTGGATACTAATATTTGTATCTCTATCACTAAGCATCAACCTGAAATTGTCCGTCAGCATTT
TGAAAAGCATTTGCCAAACCGTAACATTTTAATGTCAGTGATTACTTTAGGCGAGTTACGTTTTGGTGCTGAAAAGAGTC
AAAACAAAGAAAAAGCTTTAAAAGTCATAGATGAATTAACTTCAATCATTCCTGTTGTTGAACTGGATGAAACAGTCGCT
GAACACTATGCACAAATACGAAAAGACTTAACTTTAAAAGGTCAGATTATAGGAAACAATGATTTGTGGCTTGCAGCGCA
TGCAAGAGCAAATGATTGGGTTATGGTGACCAATAATGAAAAAGAATTTTTACGAGTTGATCAATTAAAAATAGAAAATT
GGGTAACAAAAGCGATTTAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 9058.32 Da        Isoelectric Point: 4.5718

>AT111123 WP_087513979.1 NZ_CP032134:c2890602-2890372 [Acinetobacter chinensis]
MTTAKVFMTGRSQAIRLPKEFRFEGKEVEIFRRGDEVILREKPVTADYLFKVLAQMPDDFYAEERVDEPPQEREEF

Download         Length: 231 bp

>AT111123 NZ_CP032134:c2890602-2890372 [Acinetobacter chinensis]
ATGACTACAGCAAAAGTTTTTATGACAGGACGCAGTCAAGCCATTCGTTTACCGAAAGAATTTCGCTTTGAAGGAAAAGA
AGTCGAAATCTTTCGACGTGGCGATGAGGTCATATTGCGTGAAAAACCTGTGACAGCAGACTATTTGTTTAAAGTATTGG
CACAGATGCCTGATGACTTCTATGCAGAAGAAAGAGTGGATGAACCACCACAGGAACGAGAAGAGTTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References