Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1803903..1805032 Replicon chromosome
Accession NZ_CP032134
Organism Acinetobacter chinensis strain WCHAc010005

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag CDG60_RS09415 Protein ID WP_087514209.1
Coordinates 1803903..1804664 (-) Length 254 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag CDG60_RS09420 Protein ID WP_087514210.1
Coordinates 1804661..1805032 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDG60_RS09385 1799172..1799708 - 537 WP_087514075.1 hypothetical protein -
CDG60_RS09390 1799866..1800141 - 276 WP_193853177.1 hypothetical protein -
CDG60_RS09395 1800215..1801347 - 1133 Protein_1662 IS3-like element ISAba14 family transposase -
CDG60_RS18300 1801397..1801687 - 291 WP_087514205.1 hypothetical protein -
CDG60_RS09400 1801848..1802309 - 462 WP_087514206.1 hypothetical protein -
CDG60_RS09405 1802378..1802836 - 459 WP_087514207.1 DUF4265 domain-containing protein -
CDG60_RS09410 1803169..1803885 - 717 WP_087514208.1 SGNH/GDSL hydrolase family protein -
CDG60_RS09415 1803903..1804664 - 762 WP_087514209.1 RES family NAD+ phosphorylase Toxin
CDG60_RS09420 1804661..1805032 - 372 WP_087514210.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
CDG60_RS09425 1805245..1805988 - 744 WP_087514211.1 SDR family oxidoreductase -
CDG60_RS09430 1806002..1806700 - 699 WP_087514212.1 phosphoglycerate mutase family protein -
CDG60_RS09435 1806697..1807818 - 1122 WP_087514213.1 phosphotransferase family protein -
CDG60_RS09440 1807928..1809166 - 1239 WP_087514214.1 acyl-CoA dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(64-201)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(73-121)


Sequences

Toxin        


Download         Length: 254 a.a.        Molecular weight: 28737.74 Da        Isoelectric Point: 6.4886

>T111122 WP_087514209.1 NZ_CP032134:c1804664-1803903 [Acinetobacter chinensis]
MTAVLDLWQECHGQQQIKPIAGTLYRLVESQEQIATRQLVDTLEEQALLEDLLESVKPPYPADIEKLHYLLKSPFRYPPL
KWGSRYGRTFEPSIFYGGCSVAVTLAESAYYRFVFLKSMQGTPVKSMIRSEHTLFSVGYKCKKGLRLQDVPFDRHLELLA
HPKNYAYSQALGTSMREAGIEAFEYPSARDENHAACVGLFSAQYFTGNSPQSREQWFCDVSANDVVFKAVESATIVRFEL
SQFLQQGQFPLPA

Download         Length: 762 bp

>T111122 NZ_CP032134:c1804664-1803903 [Acinetobacter chinensis]
ATGACCGCTGTACTTGATCTATGGCAGGAATGTCATGGACAGCAACAGATCAAGCCTATAGCAGGTACGCTGTACAGACT
TGTAGAAAGTCAGGAACAGATTGCAACCCGACAGCTTGTCGATACACTGGAAGAACAGGCTTTACTGGAGGATTTACTCG
AATCAGTGAAGCCACCCTATCCAGCAGATATAGAAAAACTTCATTACCTGCTGAAATCACCATTCAGGTATCCACCTTTA
AAATGGGGTTCACGCTATGGAAGGACTTTTGAACCGAGTATTTTTTATGGCGGATGCAGCGTAGCAGTTACCCTTGCAGA
GTCTGCATACTATCGTTTTGTATTCCTGAAATCCATGCAGGGAACACCTGTAAAAAGTATGATACGCTCAGAACATACTT
TATTTTCAGTGGGCTATAAGTGTAAAAAAGGTCTTCGTTTACAGGATGTACCTTTTGACAGGCATCTGGAACTGTTGGCT
CACCCTAAAAATTATGCTTATTCACAGGCTTTAGGTACATCCATGCGTGAAGCAGGTATTGAAGCGTTTGAATATCCATC
TGCGCGGGATGAAAATCATGCAGCCTGTGTTGGATTGTTCAGTGCTCAATATTTTACAGGAAACAGCCCTCAGAGCAGAG
AACAGTGGTTCTGTGATGTTTCTGCAAATGATGTTGTATTTAAAGCGGTGGAAAGTGCAACAATCGTCCGTTTTGAACTG
TCTCAGTTTTTGCAGCAAGGACAATTTCCTTTACCTGCCTGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13365.71 Da        Isoelectric Point: 10.0447

>AT111122 WP_087514210.1 NZ_CP032134:c1805032-1804661 [Acinetobacter chinensis]
MSALLKQPVEKNVVLAKAVLNAAEQLELKQTQLAAILGVHRTAISRLKSNPELDPSSKQGELALLLIRIYRALYALAGGD
LEWMRHFINTPNLVTGGVPVQQIESITGLVSVVNFLDALRGKV

Download         Length: 372 bp

>AT111122 NZ_CP032134:c1805032-1804661 [Acinetobacter chinensis]
ATGAGTGCATTACTGAAACAACCTGTAGAAAAAAATGTCGTTCTGGCAAAAGCTGTACTGAATGCAGCAGAACAGCTGGA
ACTGAAACAGACACAGCTGGCTGCCATTTTAGGTGTCCACCGTACTGCCATCAGTCGTTTAAAAAGTAATCCTGAGCTTG
ATCCATCATCCAAGCAGGGTGAACTGGCACTGTTGTTGATTCGTATTTACCGTGCGCTTTATGCTCTGGCGGGTGGCGAT
CTGGAGTGGATGCGTCATTTTATCAATACGCCGAACCTGGTCACAGGTGGTGTACCTGTACAGCAGATTGAAAGCATCAC
AGGTCTGGTCAGCGTGGTCAATTTCCTTGATGCGCTGCGGGGTAAAGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References