Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1228419..1228947 Replicon chromosome
Accession NZ_CP032098
Organism Malaciobacter molluscorum LMG 25693 strain CECT 7696

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AMOL_RS06210 Protein ID WP_099341262.1
Coordinates 1228419..1228688 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AMOL_RS06215 Protein ID WP_099341263.1
Coordinates 1228681..1228947 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMOL_RS06175 1223991..1224407 - 417 WP_099341255.1 hypothetical protein -
AMOL_RS06180 1224404..1224580 - 177 WP_099341256.1 helix-turn-helix domain-containing protein -
AMOL_RS06185 1224765..1225136 + 372 WP_099341257.1 helix-turn-helix domain-containing protein -
AMOL_RS06190 1225136..1225462 + 327 WP_099341258.1 DUF3820 family protein -
AMOL_RS06195 1225467..1226150 + 684 WP_099341259.1 hypothetical protein -
AMOL_RS06200 1226156..1227322 + 1167 WP_099341260.1 DUF3820 family protein -
AMOL_RS06205 1227384..1228298 + 915 WP_099341261.1 hypothetical protein -
AMOL_RS06210 1228419..1228688 - 270 WP_099341262.1 type II toxin-antitoxin system YafQ family toxin Toxin
AMOL_RS06215 1228681..1228947 - 267 WP_099341263.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
AMOL_RS06220 1229006..1230094 - 1089 WP_099341264.1 tyrosine-type recombinase/integrase -
AMOL_RS06225 1230507..1231355 + 849 WP_099341265.1 sel1 repeat family protein -
AMOL_RS06230 1231413..1232798 - 1386 WP_099341266.1 chemotaxis protein -
AMOL_RS06235 1232843..1233172 - 330 WP_099341312.1 hypothetical protein -
AMOL_RS06240 1233365..1233919 - 555 WP_099341267.1 HPP family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(12-87)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10348.92 Da        Isoelectric Point: 9.7586

>T111106 WP_099341262.1 NZ_CP032098:c1228688-1228419 [Malaciobacter molluscorum LMG 25693]
VLEIEVHKTFTKDLKKAQLNTTNSAKLFKYISLLQNNKELPPQARDHFLTGEYKDTKEFHISGDLIVIYINTGYTLQLLR
IGTHSQLFR

Download         Length: 270 bp

>T111106 NZ_CP032098:c1228688-1228419 [Malaciobacter molluscorum LMG 25693]
GTGCTTGAGATAGAAGTTCATAAAACATTTACAAAAGATTTAAAAAAAGCTCAACTAAATACAACAAATAGTGCAAAGTT
ATTTAAATATATTTCATTACTTCAAAATAATAAAGAATTACCTCCTCAAGCAAGAGATCACTTTTTGACAGGAGAATATA
AAGATACTAAAGAGTTTCATATAAGTGGAGATCTTATTGTAATATATATAAATACCGGATATACTTTGCAACTTCTTAGA
ATTGGTACACATTCTCAACTTTTTAGATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9911.38 Da        Isoelectric Point: 9.5159

>AT111106 WP_099341263.1 NZ_CP032098:c1228947-1228681 [Malaciobacter molluscorum LMG 25693]
MTATSNKKRTNVYLDADTKMKAQEIFKQYGLGLSEAFNIFLTQSVLERGIPFEIKIPNEETAKAIKDARSNKNMSKIDLD
DLKKDLGA

Download         Length: 267 bp

>AT111106 NZ_CP032098:c1228947-1228681 [Malaciobacter molluscorum LMG 25693]
ATGACTGCAACATCAAATAAAAAAAGAACTAATGTTTATCTTGATGCAGATACAAAAATGAAAGCTCAAGAAATATTTAA
ACAATATGGATTAGGGTTAAGTGAAGCTTTTAATATTTTTTTAACTCAATCAGTTTTAGAAAGAGGAATTCCTTTTGAAA
TAAAAATTCCAAATGAAGAAACTGCAAAAGCTATAAAAGATGCTAGATCAAATAAAAATATGTCTAAAATTGATTTGGAT
GATTTAAAAAAGGATTTAGGTGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References