Detailed information of TA system TA111106

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 1228419..1228947
• Replicon: chromosome
• Accession: NZ_CP032098
• Organism: Malaciobacter molluscorum LMG 25693 strain CECT 7696

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AMOL_RS06210
• Protein ID: WP_099341262.1
• Coordinates: 1228419..1228688 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: AMOL_RS06215
• Protein ID: WP_099341263.1
• Coordinates: 1228681..1228947 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AMOL_RS06175	1223991..1224407	-	417	WP_099341255.1	hypothetical protein	-
AMOL_RS06180	1224404..1224580	-	177	WP_099341256.1	helix-turn-helix domain-containing protein	-
AMOL_RS06185	1224765..1225136	+	372	WP_099341257.1	helix-turn-helix domain-containing protein	-
AMOL_RS06190	1225136..1225462	+	327	WP_099341258.1	DUF3820 family protein	-
AMOL_RS06195	1225467..1226150	+	684	WP_099341259.1	hypothetical protein	-
AMOL_RS06200	1226156..1227322	+	1167	WP_099341260.1	DUF3820 family protein	-
AMOL_RS06205	1227384..1228298	+	915	WP_099341261.1	hypothetical protein	-
AMOL_RS06210	1228419..1228688	-	270	WP_099341262.1	type II toxin-antitoxin system YafQ family toxin	Toxin
AMOL_RS06215	1228681..1228947	-	267	WP_099341263.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
AMOL_RS06220	1229006..1230094	-	1089	WP_099341264.1	tyrosine-type recombinase/integrase	-
AMOL_RS06225	1230507..1231355	+	849	WP_099341265.1	sel1 repeat family protein	-
AMOL_RS06230	1231413..1232798	-	1386	WP_099341266.1	chemotaxis protein	-
AMOL_RS06235	1232843..1233172	-	330	WP_099341312.1	hypothetical protein	-
AMOL_RS06240	1233365..1233919	-	555	WP_099341267.1	HPP family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-88)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (12-87)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10348.92 Da
• Isoelectric Point: 9.7586

>T111106 WP_099341262.1 NZ_CP032098:c1228688-1228419 [Malaciobacter molluscorum LMG 25693]
VLEIEVHKTFTKDLKKAQLNTTNSAKLFKYISLLQNNKELPPQARDHFLTGEYKDTKEFHISGDLIVIYINTGYTLQLLR
IGTHSQLFR

Nucleotide

• Length: 270 bp

>T111106 NZ_CP032098:c1228688-1228419 [Malaciobacter molluscorum LMG 25693]
GTGCTTGAGATAGAAGTTCATAAAACATTTACAAAAGATTTAAAAAAAGCTCAACTAAATACAACAAATAGTGCAAAGTT
ATTTAAATATATTTCATTACTTCAAAATAATAAAGAATTACCTCCTCAAGCAAGAGATCACTTTTTGACAGGAGAATATA
AAGATACTAAAGAGTTTCATATAAGTGGAGATCTTATTGTAATATATATAAATACCGGATATACTTTGCAACTTCTTAGA
ATTGGTACACATTCTCAACTTTTTAGATAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9911.38 Da
• Isoelectric Point: 9.5159

>AT111106 WP_099341263.1 NZ_CP032098:c1228947-1228681 [Malaciobacter molluscorum LMG 25693]
MTATSNKKRTNVYLDADTKMKAQEIFKQYGLGLSEAFNIFLTQSVLERGIPFEIKIPNEETAKAIKDARSNKNMSKIDLD
DLKKDLGA

Nucleotide

• Length: 267 bp

>AT111106 NZ_CP032098:c1228947-1228681 [Malaciobacter molluscorum LMG 25693]
ATGACTGCAACATCAAATAAAAAAAGAACTAATGTTTATCTTGATGCAGATACAAAAATGAAAGCTCAAGAAATATTTAA
ACAATATGGATTAGGGTTAAGTGAAGCTTTTAATATTTTTTTAACTCAATCAGTTTTAGAAAGAGGAATTCCTTTTGAAA
TAAAAATTCCAAATGAAGAAACTGCAAAAGCTATAAAAGATGCTAGATCAAATAAAAATATGTCTAAAATTGATTTGGAT
GATTTAAAAAAGGATTTAGGTGCTTGA