Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2391038..2391614 Replicon chromosome
Accession NZ_CP032097
Organism Arcobacter ellisii strain LMG 26155

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AELL_RS12150 Protein ID WP_118918207.1
Coordinates 2391315..2391614 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AELL_RS12145 Protein ID WP_014473653.1
Coordinates 2391038..2391322 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AELL_RS12125 2388488..2388979 + 492 WP_118918203.1 SHOCT domain-containing protein -
AELL_RS12130 2388997..2389440 - 444 WP_118918204.1 hypothetical protein -
AELL_RS12135 2389530..2389907 + 378 WP_118918205.1 hypothetical protein -
AELL_RS12140 2389995..2390948 + 954 WP_118918206.1 NERD domain-containing protein -
AELL_RS12145 2391038..2391322 - 285 WP_014473653.1 putative addiction module antidote protein Antitoxin
AELL_RS12150 2391315..2391614 - 300 WP_118918207.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AELL_RS12155 2391669..2392148 - 480 WP_118918208.1 hypothetical protein -
AELL_RS12160 2392150..2392974 - 825 WP_118918209.1 metallophosphoesterase -
AELL_RS12165 2392971..2393282 - 312 WP_118918662.1 hypothetical protein -
AELL_RS12170 2393657..2393986 - 330 WP_014473649.1 hypothetical protein -
AELL_RS12175 2394316..2395026 + 711 WP_118918210.1 hypothetical protein -
AELL_RS12180 2395100..2395510 + 411 WP_118918211.1 hypothetical protein -
AELL_RS14330 2395503..2395640 + 138 WP_164967262.1 hypothetical protein -
AELL_RS12185 2395643..2396563 + 921 WP_118918212.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11340.07 Da        Isoelectric Point: 9.6938

>T111105 WP_118918207.1 NZ_CP032097:c2391614-2391315 [Arcobacter ellisii]
MYLIKQTNIFSKWLLKLKDTQGKVAVLRRVERMKLGNFGDHKSVGNNISELRIPTGPGYRVYYTQKDDEIIVLLVGGDKS
SQSDDIKKANEILKELENE

Download         Length: 300 bp

>T111105 NZ_CP032097:c2391614-2391315 [Arcobacter ellisii]
ATGTATTTAATAAAACAAACAAATATCTTTTCAAAATGGTTGTTAAAGCTCAAAGATACTCAAGGTAAAGTTGCAGTATT
ACGAAGAGTTGAGAGAATGAAATTAGGAAACTTTGGAGACCATAAATCAGTTGGTAATAATATAAGTGAACTTAGAATTC
CAACAGGTCCAGGATATAGAGTTTACTATACTCAAAAAGATGATGAAATTATTGTTTTATTAGTTGGTGGTGATAAATCA
TCACAAAGTGATGATATTAAAAAAGCAAATGAGATTTTAAAGGAGCTTGAAAATGAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10267.81 Da        Isoelectric Point: 4.7672

>AT111105 WP_014473653.1 NZ_CP032097:c2391322-2391038 [Arcobacter ellisii]
MSNVELTNFDIAQYLDNKEVIAEYLSQILADGDMDELLEALGNIAKAKGMSQIASETGLGRESLYKTFHKGTKPKFDTIM
KILGSLGVKVQVTA

Download         Length: 285 bp

>AT111105 NZ_CP032097:c2391322-2391038 [Arcobacter ellisii]
ATGAGTAATGTAGAACTTACAAACTTTGATATAGCACAATATCTTGATAATAAAGAAGTAATAGCAGAATACCTATCTCA
AATCTTAGCAGATGGTGATATGGATGAATTACTAGAAGCTCTTGGAAATATTGCAAAAGCAAAAGGTATGAGCCAAATTG
CAAGTGAAACAGGATTAGGTAGAGAAAGTTTATATAAAACTTTTCATAAAGGCACAAAACCTAAATTTGACACTATTATG
AAAATACTTGGTTCACTTGGAGTTAAAGTTCAAGTTACTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References