Detailed information of TA system TA111104

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2257831..2258356
• Replicon: chromosome
• Accession: NZ_CP032097
• Organism: Arcobacter ellisii strain LMG 26155

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AELL_RS11450
• Protein ID: WP_118918086.1
• Coordinates: 2257831..2258115 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: AELL_RS11455
• Protein ID: WP_118918087.1
• Coordinates: 2258105..2258356 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AELL_RS11425	2253402..2253728	-	327	WP_118918081.1	HipA N-terminal domain-containing protein	-
AELL_RS11430	2253728..2253940	-	213	WP_118918082.1	helix-turn-helix domain-containing protein	-
AELL_RS11435	2254234..2254611	-	378	WP_118918083.1	hypothetical protein	-
AELL_RS11440	2254613..2255893	-	1281	WP_118918084.1	HipA domain-containing protein	-
AELL_RS11445	2256343..2257557	-	1215	WP_118918085.1	ATP-binding protein	-
AELL_RS11450	2257831..2258115	-	285	WP_118918086.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AELL_RS11455	2258105..2258356	-	252	WP_118918087.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
AELL_RS11460	2258644..2259855	-	1212	WP_118918088.1	tyrosine-type recombinase/integrase	-
AELL_RS11475	2260393..2261091	-	699	WP_118918089.1	orotidine-5'-phosphate decarboxylase	-
AELL_RS11480	2261095..2261490	-	396	WP_118918090.1	transcription antitermination factor NusB	-
AELL_RS11485	2261493..2261963	-	471	WP_118918091.1	6,7-dimethyl-8-ribityllumazine synthase	-
AELL_RS11490	2261993..2262793	-	801	WP_118918092.1	3-deoxy-8-phosphooctulonate synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (11-73)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11259.19 Da
• Isoelectric Point: 10.2762

>T111104 WP_118918086.1 NZ_CP032097:c2258115-2257831 [Arcobacter ellisii]
MTYNLEFKPQALKEWSKLASTIKEQFKKKLEERLQNPKVEKDKLSGYENVYKIKLKTLGYRLAYQVKDEEIVVLVLSVGK
REKDKIYKNTKDRF

Nucleotide

• Length: 285 bp

>T111104 NZ_CP032097:c2258115-2257831 [Arcobacter ellisii]
ATGACTTATAATCTTGAATTTAAACCTCAAGCTTTAAAAGAATGGAGTAAATTAGCTTCAACAATAAAAGAGCAATTTAA
AAAGAAATTAGAAGAAAGATTACAAAATCCAAAAGTAGAAAAAGATAAACTAAGTGGATATGAAAATGTTTATAAAATAA
AATTAAAAACTTTGGGATATAGACTTGCTTATCAAGTTAAAGATGAAGAGATTGTTGTTTTAGTATTAAGTGTTGGAAAA
AGAGAAAAAGATAAAATTTACAAGAATACAAAAGATAGATTCTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9270.69 Da
• Isoelectric Point: 4.3696

>AT111104 WP_118918087.1 NZ_CP032097:c2258356-2258105 [Arcobacter ellisii]
MQPILANYSASITELKKSPTQLLNEADNEVIAILNHNIPCAYLVPSKLYEKMMDIIDDYHLSLEVAKALNDGEKPVKVSL
DDL

Nucleotide

• Length: 252 bp

>AT111104 NZ_CP032097:c2258356-2258105 [Arcobacter ellisii]
ATGCAACCAATTTTAGCAAATTATAGTGCAAGTATAACAGAACTTAAAAAATCTCCTACACAATTATTAAATGAAGCTGA
TAATGAAGTTATAGCAATATTAAATCATAATATCCCTTGTGCCTATTTAGTCCCAAGTAAATTGTATGAAAAAATGATGG
ATATTATAGATGATTATCATTTGTCATTAGAAGTTGCAAAAGCTTTAAATGATGGTGAAAAACCAGTTAAAGTAAGTTTA
GATGACTTATAA