Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 62969..63485 Replicon plasmid pVa1
Accession NZ_CP032095
Organism Vibrio alfacsensis strain CAIM 1831

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag D1115_RS22525 Protein ID WP_128813577.1
Coordinates 63216..63485 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag D1115_RS22520 Protein ID WP_128813576.1
Coordinates 62969..63223 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1115_RS22500 58078..59148 + 1071 WP_128813572.1 acyl-CoA/acyl-ACP dehydrogenase -
D1115_RS22505 59148..60299 + 1152 WP_128813573.1 acetyl-CoA C-acetyltransferase -
D1115_RS22510 60356..61234 + 879 WP_128813574.1 SDR family oxidoreductase -
D1115_RS22515 61236..62825 + 1590 WP_128813575.1 amidase -
D1115_RS22520 62969..63223 + 255 WP_128813576.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
D1115_RS22525 63216..63485 + 270 WP_128813577.1 Txe/YoeB family addiction module toxin Toxin
D1115_RS22530 63548..63880 - 333 WP_128813578.1 SEC-C domain-containing protein -
D1115_RS22535 64150..64377 - 228 WP_128813579.1 hypothetical protein -
D1115_RS22540 64594..64896 - 303 Protein_60 type II toxin-antitoxin system RelE/ParE family toxin -
D1115_RS22545 64896..65156 - 261 WP_128813580.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
D1115_RS22550 66200..66409 + 210 WP_128813581.1 hypothetical protein -
D1115_RS22560 66859..68223 + 1365 WP_128813583.1 endonuclease/exonuclease/phosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..176380 176380


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10658.08 Da        Isoelectric Point: 9.4087

>T111102 WP_128813577.1 NZ_CP032095:63216-63485 [Vibrio alfacsensis]
MSSHQRLLAWTDEAWNDYLYWQNQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLAGFWSRRIDDTNRLVYAVDNQAI
TIISCRYHY

Download         Length: 270 bp

>T111102 NZ_CP032095:63216-63485 [Vibrio alfacsensis]
ATGAGTAGTCACCAGCGTTTGCTCGCTTGGACTGACGAAGCTTGGAATGACTACCTGTATTGGCAAAATCAGGACAAGAA
AACACTCAAGCGTATCAATAAATTAATTAATGATGTAAAGCGCTCGCCCTTTGAGGGGATTGGTAAACCAGAGCCTTTAA
AAGAGAACCTGGCGGGTTTCTGGTCACGTCGCATTGATGATACCAATCGTCTCGTTTACGCGGTCGATAACCAGGCGATA
ACCATTATTTCTTGCCGTTACCATTATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9498.64 Da        Isoelectric Point: 4.7640

>AT111102 WP_128813576.1 NZ_CP032095:62969-63223 [Vibrio alfacsensis]
MRIVSFTEARNSLKAVLDGVVNDADTTIITRRDSEDAVVMSLDYYNSLMETVHLLRSPENADHLKRSIAQYRAGQVTSRD
LIDE

Download         Length: 255 bp

>AT111102 NZ_CP032095:62969-63223 [Vibrio alfacsensis]
ATGAGAATCGTATCTTTTACTGAAGCACGAAATAGTTTAAAAGCGGTGTTAGACGGTGTGGTTAATGATGCTGACACGAC
GATCATTACGCGGAGAGACTCAGAAGATGCTGTGGTGATGTCATTAGATTATTACAACAGTTTGATGGAAACGGTGCACT
TACTGCGTTCTCCAGAGAACGCGGATCATCTCAAGCGTTCAATCGCTCAATATCGTGCTGGCCAAGTGACTTCTCGAGAC
TTAATTGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References