110919

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 3357505..3358018 Replicon chromosome
Accession NZ_CP032002
Organism Acinetobacter haemolyticus strain 11616

Toxin (Protein)


Gene name yoeB Uniprot ID A0A558EQR2
Locus tag Ahae11616_RS16125 Protein ID WP_043975117.1
Coordinates 3357755..3358018 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S7WSW9
Locus tag Ahae11616_RS16120 Protein ID WP_000557943.1
Coordinates 3357505..3357768 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Ahae11616_RS16110 3353041..3353724 + 684 Protein_3129 HipA domain-containing protein -
Ahae11616_RS16115 3353742..3357089 - 3348 WP_160124307.1 DEAD/DEAH box helicase -
Ahae11616_RS16120 3357505..3357768 + 264 WP_000557943.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Ahae11616_RS16125 3357755..3358018 + 264 WP_043975117.1 Txe/YoeB family addiction module toxin Toxin
Ahae11616_RS16130 3358090..3358245 - 156 Protein_3133 IS5/IS1182 family transposase -
Ahae11616_RS16135 3358291..3358623 - 333 Protein_3134 transposase -
Ahae11616_RS16140 3358946..3360298 - 1353 WP_160124308.1 MHS family MFS transporter -
Ahae11616_RS16145 3360417..3361442 - 1026 WP_160124309.1 enoyl-CoA hydratase/isomerase family protein -
Ahae11616_RS16150 3361455..3362228 - 774 WP_160124310.1 enoyl-CoA hydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10680.10 Da        Isoelectric Point: 7.8508

>T110919 WP_043975117.1 NZ_CP032002:3357755-3358018 [Acinetobacter haemolyticus]
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
VQCWFHY

Download         Length: 264 bp

>T110919 NZ_CP032002:3357755-3358018 [Acinetobacter haemolyticus]
ATGACGAGTCGTAATGTCGAATGGACTGAAAATGCCTGGGATGAATATATCTATTGGCAAACACAGGATAAAAAGATACT
CAAACGTATCAATACCTTAATCAGAGAATGTCAAAGAACACCCTTTGAAGGAACTGGAAAACCAGAACCTTTAAAAGCAA
ATCTTTCAGGATTCTGGAGCCGTAGAATTGATGAGAAGCATAGATTAGTTTATGAAGTGACGGATGAACGAATTTCCATT
GTTCAATGTTGGTTCCATTACTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9841.04 Da        Isoelectric Point: 5.5940

>AT110919 WP_000557943.1 NZ_CP032002:3357505-3357768 [Acinetobacter haemolyticus]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES

Download         Length: 264 bp

>AT110919 NZ_CP032002:3357505-3357768 [Acinetobacter haemolyticus]
ATGCATGTATTTACATATACAGACGCACGTAACAACTTAAAATCTGTTTTAGATAAAGTTATTGATGATGCAGATGTCGC
TTTCATTACAAGAAAAGAAGGCGGTCATGCTGTAGTAATGGGACAAGATCATTACGACAGTTTAATGGAAACGTTGTATC
TCCTTTCATCTCCAAATAATACCACTCGTTTAAACGAATCAATTGCTCAATTACGCGCAGGTAAAACCAAACAAAGAGAG
TTGATTAAAGATGACGAGTCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A558EQR2

Antitoxin

Source ID Structure
AlphaFold DB S7WSW9

References