Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 3420471..3420984 Replicon chromosome
Accession NZ_CP031991
Organism Acinetobacter haemolyticus strain 2126ch

Toxin (Protein)


Gene name yoeB Uniprot ID A0A558EQR2
Locus tag Ahae2126ch_RS16490 Protein ID WP_043975117.1
Coordinates 3420721..3420984 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S7WSW9
Locus tag Ahae2126ch_RS16485 Protein ID WP_000557943.1
Coordinates 3420471..3420734 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Ahae2126ch_RS16475 3415998..3416690 + 693 WP_198421056.1 HipA domain-containing protein -
Ahae2126ch_RS16480 3416708..3420055 - 3348 WP_160140411.1 DEAD/DEAH box helicase -
Ahae2126ch_RS16485 3420471..3420734 + 264 WP_000557943.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Ahae2126ch_RS16490 3420721..3420984 + 264 WP_043975117.1 Txe/YoeB family addiction module toxin Toxin
Ahae2126ch_RS16495 3421056..3421211 - 156 Protein_3205 IS5/IS1182 family transposase -
Ahae2126ch_RS16500 3421257..3421589 - 333 Protein_3206 transposase -
Ahae2126ch_RS16505 3421900..3422223 - 324 Protein_3207 GNAT family N-acetyltransferase -
Ahae2126ch_RS16510 3422296..3423386 + 1091 WP_085947913.1 IS4-like element ISAba1 family transposase -
Ahae2126ch_RS16520 3423679..3425031 - 1353 WP_005092610.1 MHS family MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3359032..3421857 62825


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10680.10 Da        Isoelectric Point: 7.8508

>T110903 WP_043975117.1 NZ_CP031991:3420721-3420984 [Acinetobacter haemolyticus]
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
VQCWFHY

Download         Length: 264 bp

>T110903 NZ_CP031991:3420721-3420984 [Acinetobacter haemolyticus]
ATGACGAGTCGTAATGTCGAATGGACTGAAAATGCCTGGGATGAATATATCTATTGGCAAACACAGGATAAAAAGATACT
CAAACGTATCAATACCTTAATCAGAGAATGTCAAAGAACACCCTTTGAAGGAACTGGAAAACCAGAACCTTTAAAAGCAA
ATCTTTCAGGATTCTGGAGCCGTAGAATTGATGAGAAGCATAGATTAGTTTATGAAGTGACGGATGAACGAATTTCCATT
GTTCAATGTTGGTTCCATTACTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9841.04 Da        Isoelectric Point: 5.5940

>AT110903 WP_000557943.1 NZ_CP031991:3420471-3420734 [Acinetobacter haemolyticus]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES

Download         Length: 264 bp

>AT110903 NZ_CP031991:3420471-3420734 [Acinetobacter haemolyticus]
ATGCATGTATTTACATATACAGACGCACGTAACAACTTAAAATCTGTTTTAGATAAAGTTATTGATGATGCAGATGTCGC
TTTCATTACAAGAAAAGAAGGCGGTCATGCTGTAGTAATGGGACAAGATCATTACGACAGTTTAATGGAAACGTTGTATC
TCCTTTCATCTCCAAATAATACCACTCGTTTAAACGAATCAATTGCTCAATTACGCGCAGGTAAAACCAAACAAAGAGAG
TTGATTAAAGATGACGAGTCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A558EQR2

Antitoxin

Source ID Structure
AlphaFold DB S7WSW9

References