Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 439712..440351 Replicon chromosome
Accession NZ_CP031984
Organism Acinetobacter haemolyticus strain AN3

Toxin (Protein)


Gene name cptA Uniprot ID C0VNL5
Locus tag AhaeAN3_RS02160 Protein ID WP_005088316.1
Coordinates 439956..440351 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N9FB90
Locus tag AhaeAN3_RS02155 Protein ID WP_004641025.1
Coordinates 439712..439969 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AhaeAN3_RS02130 434790..435155 + 366 WP_004641032.1 50S ribosomal protein L17 -
AhaeAN3_RS02135 435316..435813 + 498 WP_075316485.1 GNAT family N-acetyltransferase -
AhaeAN3_RS02140 436191..437681 + 1491 WP_075314692.1 NAD(P)/FAD-dependent oxidoreductase -
AhaeAN3_RS02145 437804..438301 + 498 WP_005088321.1 DUF2059 domain-containing protein -
AhaeAN3_RS02150 438353..439525 - 1173 WP_005086825.1 acyl-CoA dehydrogenase family protein -
AhaeAN3_RS02155 439712..439969 + 258 WP_004641025.1 succinate dehydrogenase assembly factor 2 Antitoxin
AhaeAN3_RS02160 439956..440351 + 396 WP_005088316.1 hypothetical protein Toxin
AhaeAN3_RS02165 440562..440768 + 207 WP_171261742.1 hypothetical protein -
AhaeAN3_RS02170 441128..442171 + 1044 WP_075314696.1 hypothetical protein -
AhaeAN3_RS02175 442299..442880 + 582 WP_004641018.1 rhombosortase -
AhaeAN3_RS02180 443058..445268 + 2211 WP_004641016.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 445312..446469 1157


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 16153.44 Da        Isoelectric Point: 9.1954

>T110890 WP_005088316.1 NZ_CP031984:439956-440351 [Acinetobacter haemolyticus]
MSTADRVFVLKRSRFAFAFQLFIFIVLISLLYYLLPWFLWLVSFPLMLIAWVLLLKQPQLKHFEYLDDQLCSLCFSDEMQ
RIEQRKIRKMIDHQCYIVIYFYDSQCRPCVIWWDQLSILQWKKLRTWVKLA

Download         Length: 396 bp

>T110890 NZ_CP031984:439956-440351 [Acinetobacter haemolyticus]
ATGTCCACGGCTGATCGTGTTTTTGTGTTGAAACGCAGTCGTTTTGCATTTGCGTTTCAACTTTTTATTTTTATCGTACT
GATCAGTTTATTGTATTACTTACTTCCTTGGTTTTTATGGCTTGTTAGCTTTCCTTTGATGCTAATTGCTTGGGTATTAT
TACTCAAACAACCTCAGCTTAAACACTTTGAATATTTAGATGATCAGCTTTGCTCCTTGTGTTTTAGTGATGAGATGCAG
AGGATCGAGCAAAGGAAAATTCGAAAAATGATCGATCATCAATGTTATATCGTCATCTATTTTTATGACTCTCAATGTCG
ACCTTGTGTGATTTGGTGGGATCAATTGTCGATTTTACAGTGGAAAAAGCTCAGAACATGGGTCAAACTTGCATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9982.42 Da        Isoelectric Point: 4.4558

>AT110890 WP_004641025.1 NZ_CP031984:439712-439969 [Acinetobacter haemolyticus]
MSEELTLEERKVIYRARRGLKEIDVYFDPYVKNCYLTADAAEKALFAELVDQEDPDLLDWFMEVGEPPRPELKAFISKLK
QYVHG

Download         Length: 258 bp

>AT110890 NZ_CP031984:439712-439969 [Acinetobacter haemolyticus]
ATGTCTGAAGAATTGACACTAGAAGAACGTAAAGTGATTTATCGTGCGCGTCGTGGTTTGAAAGAAATCGATGTGTATTT
TGATCCTTATGTTAAAAATTGTTATCTCACAGCAGATGCGGCTGAGAAAGCATTGTTTGCAGAGTTGGTAGATCAAGAAG
ATCCTGATTTACTGGATTGGTTCATGGAGGTGGGTGAACCTCCTCGTCCAGAGTTAAAAGCGTTTATTTCAAAATTAAAA
CAGTATGTCCACGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1L6KJV0

Antitoxin

Source ID Structure
AlphaFold DB N9FB90

References