110886

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 3410606..3411119 Replicon chromosome
Accession NZ_CP031979
Organism Acinetobacter haemolyticus strain AN4

Toxin (Protein)


Gene name yoeB Uniprot ID A0A558EQR2
Locus tag AhaeAN4_RS16660 Protein ID WP_043975117.1
Coordinates 3410856..3411119 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S7WSW9
Locus tag AhaeAN4_RS16655 Protein ID WP_000557943.1
Coordinates 3410606..3410869 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AhaeAN4_RS16645 3406142..3406825 + 684 Protein_3238 HipA domain-containing protein -
AhaeAN4_RS16650 3406843..3410190 - 3348 WP_160132234.1 DEAD/DEAH box helicase -
AhaeAN4_RS16655 3410606..3410869 + 264 WP_000557943.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AhaeAN4_RS16660 3410856..3411119 + 264 WP_043975117.1 Txe/YoeB family addiction module toxin Toxin
AhaeAN4_RS16665 3411191..3411346 - 156 Protein_3242 IS5/IS1182 family transposase -
AhaeAN4_RS16670 3411392..3411724 - 333 Protein_3243 transposase -
AhaeAN4_RS16675 3412047..3413399 - 1353 WP_160124308.1 MHS family MFS transporter -
AhaeAN4_RS16680 3413518..3414543 - 1026 WP_160124309.1 enoyl-CoA hydratase/isomerase family protein -
AhaeAN4_RS16685 3414556..3415329 - 774 WP_160124310.1 enoyl-CoA hydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3343467..3413399 69932


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10680.10 Da        Isoelectric Point: 7.8508

>T110886 WP_043975117.1 NZ_CP031979:3410856-3411119 [Acinetobacter haemolyticus]
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
VQCWFHY

Download         Length: 264 bp

>T110886 NZ_CP031979:3410856-3411119 [Acinetobacter haemolyticus]
ATGACGAGTCGTAATGTCGAATGGACTGAAAATGCCTGGGATGAATATATCTATTGGCAAACACAGGATAAAAAGATACT
CAAACGTATCAATACCTTAATCAGAGAATGTCAAAGAACACCCTTTGAAGGAACTGGAAAACCAGAACCTTTAAAAGCAA
ATCTTTCAGGATTCTGGAGCCGTAGAATTGATGAGAAGCATAGATTAGTTTATGAAGTGACGGATGAACGAATTTCCATT
GTTCAATGTTGGTTCCATTACTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9841.04 Da        Isoelectric Point: 5.5940

>AT110886 WP_000557943.1 NZ_CP031979:3410606-3410869 [Acinetobacter haemolyticus]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES

Download         Length: 264 bp

>AT110886 NZ_CP031979:3410606-3410869 [Acinetobacter haemolyticus]
ATGCATGTATTTACATATACAGACGCACGTAACAACTTAAAATCTGTTTTAGATAAAGTTATTGATGATGCAGATGTCGC
TTTCATTACAAGAAAAGAAGGCGGTCATGCTGTAGTAATGGGACAAGATCATTACGACAGTTTAATGGAAACGTTGTATC
TCCTTTCATCTCCAAATAATACCACTCGTTTAAACGAATCAATTGCTCAATTACGCGCAGGTAAAACCAAACAAAGAGAG
TTGATTAAAGATGACGAGTCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A558EQR2

Antitoxin

Source ID Structure
AlphaFold DB S7WSW9

References