Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/-
Location 159316..159710 Replicon chromosome
Accession NZ_CP031970
Organism Streptococcus suis strain SFJ44

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag D2A30_RS00865 Protein ID WP_239604456.1
Coordinates 159540..159710 (+) Length 57 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag D2A30_RS10400 Protein ID WP_275577031.1
Coordinates 159316..159444 (+) Length 43 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D2A30_RS00830 (D2A30_00850) 154373..154732 + 360 WP_174846592.1 ribonuclease P protein component -
D2A30_RS00835 (D2A30_00855) 154716..155528 + 813 WP_174846591.1 YidC/Oxa1 family membrane protein insertase -
D2A30_RS00840 (D2A30_00860) 155547..156551 + 1005 WP_239604455.1 RNA-binding cell elongation regulator Jag/EloR -
D2A30_RS00845 (D2A30_00865) 156773..156910 + 138 WP_049618373.1 50S ribosomal protein L34 -
D2A30_RS00850 (D2A30_00870) 156960..157841 - 882 WP_174846590.1 diacylglycerol kinase family lipid kinase -
D2A30_RS00855 (D2A30_00875) 157991..158773 + 783 WP_171988962.1 TatD family hydrolase -
D2A30_RS00860 (D2A30_00880) 158757..159323 + 567 WP_171989046.1 ribonuclease M5 -
D2A30_RS10400 159316..159444 + 129 WP_275577031.1 hypothetical protein Antitoxin
D2A30_RS00865 (D2A30_00890) 159540..159710 + 171 WP_239604456.1 hypothetical protein Toxin
D2A30_RS00870 (D2A30_00895) 159717..159969 + 253 Protein_154 NUDIX domain-containing protein -
D2A30_RS00875 (D2A30_00900) 160008..160880 + 873 WP_171988961.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
D2A30_RS00880 (D2A30_00905) 162126..162866 + 741 WP_171988960.1 amino acid transporter -
D2A30_RS00885 (D2A30_00910) 162876..163454 + 579 WP_239604458.1 CPBP family intramembrane metalloprotease -
D2A30_RS00890 (D2A30_00915) 163466..163894 + 429 WP_171988959.1 Msa family membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-123)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(16-56)


Sequences

Toxin        


Download         Length: 57 a.a.        Molecular weight: 6555.70 Da        Isoelectric Point: 10.3173

>T110866 WP_239604456.1 NZ_CP031970:159540-159710 [Streptococcus suis]
MSFNADNRFGKQIDPLHLTRGYVIGKDYIALYRVVKNELRVVHLFATKSDYVKLLK

Download         Length: 171 bp

>T110866 NZ_CP031970:159540-159710 [Streptococcus suis]
TTGAGTTTTAACGCCGATAACCGTTTTGGTAAGCAGATAGACCCGCTTCATCTGACCCGAGGCTACGTCATTGGAAAAGA
CTACATTGCTCTCTATCGCGTAGTGAAAAATGAACTTCGAGTTGTTCACCTTTTTGCGACCAAGAGTGATTATGTTAAGT
TGTTGAAGTGA

Antitoxin


Download         Length: 43 a.a.        Molecular weight: 4753.45 Da        Isoelectric Point: 3.7141

>AT110866 WP_275577031.1 NZ_CP031970:159316-159444 [Streptococcus suis]
MSELETGKEVFAMNQLDLTASFNLILQNIAVKNELLILTEEE

Download         Length: 129 bp

>AT110866 NZ_CP031970:159316-159444 [Streptococcus suis]
ATGAGTGAATTGGAAACAGGCAAGGAAGTATTTGCTATGAACCAGCTGGATTTGACTGCTAGCTTCAATCTAATTTTACA
AAACATTGCTGTAAAAAATGAGTTGCTAATTCTGACAGAAGAAGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References