Detailed information of TA system TA110862

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-parD/RelE(toxin)
• Location: 4449064..4449617
• Replicon: chromosome
• Accession: NZ_CP031968
• Organism: Chromobacterium rhizoryzae strain JP2-74

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: D1345_RS20350
• Protein ID: WP_118268386.1
• Coordinates: 4449345..4449617 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A2T5NS08
• Locus tag: D1345_RS20345
• Protein ID: WP_019102024.1
• Coordinates: 4449064..4449348 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D1345_RS20320	4444208..4445287	+	1080	WP_019103142.1	ionic transporter y4hA	-
D1345_RS20325	4445506..4445928	-	423	WP_052051917.1	nuclear transport factor 2 family protein	-
D1345_RS20330	4445968..4446672	-	705	WP_107733028.1	DsbA family protein	-
D1345_RS20335	4446855..4447736	-	882	WP_043589989.1	MBL fold metallo-hydrolase	-
D1345_RS20340	4447865..4448779	+	915	WP_043589705.1	LysR family transcriptional regulator	-
D1345_RS20345	4449064..4449348	+	285	WP_019102024.1	hypothetical protein	Antitoxin
D1345_RS20350	4449345..4449617	+	273	WP_118268386.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
D1345_RS20355	4450161..4450610	+	450	WP_118268387.1	hypothetical protein	-
D1345_RS20360	4450725..4451639	-	915	WP_205422960.1	LysR family transcriptional regulator	-
D1345_RS20365	4451755..4452768	+	1014	WP_118268388.1	zinc-binding alcohol dehydrogenase family protein	-
D1345_RS20370	4453339..4454031	+	693	WP_019102518.1	response regulator transcription factor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10263.87 Da
• Isoelectric Point: 8.0599

>T110862 WP_118268386.1 NZ_CP031968:4449345-4449617 [Chromobacterium rhizoryzae]
MKLAWTPDAVADREAIFEYIAADNPAAALALDELFEQQASRLLLHPELGRAGRVAGTRKWVLHRNYVCVYDLVTDQLRVL
RILHVARQRP

Nucleotide

• Length: 273 bp

>T110862 NZ_CP031968:4449345-4449617 [Chromobacterium rhizoryzae]
ATGAAGCTGGCTTGGACGCCTGATGCGGTGGCGGATCGCGAAGCCATTTTTGAATACATTGCAGCAGATAACCCAGCAGC
GGCTCTTGCTCTTGATGAGCTTTTTGAGCAGCAGGCCTCCCGGCTGCTTCTGCATCCTGAGTTGGGCCGGGCAGGACGTG
TTGCCGGCACTAGAAAGTGGGTTCTTCATCGCAACTATGTCTGCGTTTACGATTTAGTAACTGATCAACTCCGGGTGCTT
CGGATTTTACATGTTGCCCGACAACGGCCTTAA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10962.27 Da
• Isoelectric Point: 5.9110

>AT110862 WP_019102024.1 NZ_CP031968:4449064-4449348 [Chromobacterium rhizoryzae]
MSESTFTFRVDESLKQEFAKVAKLQDRTGAQLLRDFMREVVRKNEEAAEYDQWFRSQVQQGLDQANAGELLPGDQVEAHF
AAKRAELRRRMAER

Nucleotide

• Length: 285 bp

>AT110862 NZ_CP031968:4449064-4449348 [Chromobacterium rhizoryzae]
ATGAGCGAGTCGACTTTTACTTTCCGTGTCGATGAGTCTCTGAAGCAGGAGTTTGCCAAGGTGGCCAAATTGCAGGATCG
CACGGGCGCCCAGCTACTCCGTGACTTTATGCGCGAAGTGGTGCGAAAGAATGAGGAGGCCGCTGAGTATGATCAGTGGT
TCCGTAGCCAGGTCCAACAGGGGCTGGACCAAGCGAATGCGGGTGAACTGCTTCCTGGCGATCAGGTAGAGGCGCATTTT
GCTGCCAAGAGGGCGGAGTTGCGCCGGAGAATGGCTGAACGATGA

Structures

Antitoxin

• AlphaFold DB: A0A2T5NS08