Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4044539..4045061 Replicon chromosome
Accession NZ_CP031968
Organism Chromobacterium rhizoryzae strain JP2-74

Toxin (Protein)


Gene name relE Uniprot ID A0A0J6NKF3
Locus tag D1345_RS18450 Protein ID WP_048414285.1
Coordinates 4044774..4045061 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0J6NMH5
Locus tag D1345_RS18445 Protein ID WP_048414286.1
Coordinates 4044539..4044784 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1345_RS18425 4039548..4040891 + 1344 WP_118268306.1 type I-F CRISPR-associated protein Csy1 -
D1345_RS18430 4040888..4041886 + 999 WP_118268307.1 type I-F CRISPR-associated protein Csy2 -
D1345_RS18435 4041899..4042936 + 1038 WP_107732825.1 type I-F CRISPR-associated protein Csy3 -
D1345_RS18440 4042940..4043497 + 558 WP_107732826.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
D1345_RS18445 4044539..4044784 + 246 WP_048414286.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
D1345_RS18450 4044774..4045061 + 288 WP_048414285.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D1345_RS18455 4045272..4047950 + 2679 WP_118268308.1 TonB-dependent receptor -
D1345_RS18475 4048377..4049603 - 1227 WP_048414282.1 aspartate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4034012..4045061 11049


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11116.86 Da        Isoelectric Point: 10.3332

>T110861 WP_048414285.1 NZ_CP031968:4044774-4045061 [Chromobacterium rhizoryzae]
MSYEIVFRVDAEKEWRKLDPSIRQQFAKKLRERAEHPHNPAAKLHGLEGCYKIKLRQTGYRLVYEVDDGKIIIIVVAIGH
RDKNQAYQKAKARQG

Download         Length: 288 bp

>T110861 NZ_CP031968:4044774-4045061 [Chromobacterium rhizoryzae]
ATGAGCTATGAAATTGTCTTCCGGGTGGATGCGGAGAAGGAATGGCGAAAGTTGGACCCATCAATCCGACAGCAGTTTGC
CAAGAAACTGAGAGAACGAGCCGAGCATCCGCACAACCCTGCCGCCAAGCTGCATGGCCTGGAAGGCTGCTACAAGATCA
AGCTGCGTCAGACCGGATACCGGCTGGTCTATGAGGTGGACGACGGCAAAATCATCATCATCGTGGTGGCTATCGGACAT
CGCGACAAGAACCAAGCCTACCAAAAAGCCAAAGCGCGCCAGGGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9186.63 Da        Isoelectric Point: 4.5972

>AT110861 WP_048414286.1 NZ_CP031968:4044539-4044784 [Chromobacterium rhizoryzae]
MDLVLADVAVSVTELKRNFAGIMREAAGHPVVILNHNRPEAYLVPAAQYERMMSLLEDIEDTKLVLERRQQPTVKVDLDE
L

Download         Length: 246 bp

>AT110861 NZ_CP031968:4044539-4044784 [Chromobacterium rhizoryzae]
ATGGACTTGGTACTTGCCGATGTGGCCGTCAGCGTCACCGAGCTCAAGCGCAATTTTGCCGGCATCATGCGCGAGGCCGC
AGGGCATCCGGTGGTGATCCTGAATCACAACCGCCCAGAGGCCTATCTTGTCCCTGCCGCCCAGTACGAACGCATGATGA
GCCTGCTTGAAGACATTGAGGACACAAAGCTGGTGTTGGAACGTCGGCAGCAGCCCACTGTCAAGGTGGACCTGGATGAG
CTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J6NKF3

Antitoxin

Source ID Structure
AlphaFold DB A0A0J6NMH5

References