Detailed information of TA system TA110859

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 1252195..1252712
• Replicon: chromosome
• Accession: NZ_CP031968
• Organism: Chromobacterium rhizoryzae strain JP2-74

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: D1345_RS05705
• Protein ID: WP_043593771.1
• Coordinates: 1252458..1252712 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: A0A2T5NK26
• Locus tag: D1345_RS05700
• Protein ID: WP_019101444.1
• Coordinates: 1252195..1252458 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D1345_RS05680	1247296..1247823	-	528	WP_043594225.1	TIGR00645 family protein	-
D1345_RS05685	1248200..1249516	+	1317	WP_107733104.1	30S ribosomal protein S12 methylthiotransferase RimO	-
D1345_RS05690	1250490..1251014	+	525	WP_152596977.1	hypothetical protein	-
D1345_RS05695	1251321..1251797	+	477	WP_039755364.1	peptidylprolyl isomerase	-
D1345_RS05700	1252195..1252458	+	264	WP_019101444.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
D1345_RS05705	1252458..1252712	+	255	WP_043593771.1	Txe/YoeB family addiction module toxin	Toxin
D1345_RS05710	1253149..1253415	+	267	Protein_1108	peptidylprolyl isomerase	-
D1345_RS05715	1253841..1254656	+	816	WP_052052248.1	FRG domain-containing protein	-
D1345_RS23820	1254812..1255543	+	732	WP_162897012.1	hypothetical protein	-
D1345_RS05725	1255736..1256302	-	567	WP_200881467.1	hypothetical protein	-
D1345_RS05730	1256488..1257162	-	675	WP_043593767.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10183.61 Da
• Isoelectric Point: 8.8727

>T110859 WP_043593771.1 NZ_CP031968:1252458-1252712 [Chromobacterium rhizoryzae]
MQIKFDDNAWEDYLYWQQSSKPTLKRINALIKDIQRNPFEGIGKPEPLKHQFAGFWSRRIDEEHRLVYAVQSNVLTILQC
RYHY

Nucleotide

• Length: 255 bp

>T110859 NZ_CP031968:1252458-1252712 [Chromobacterium rhizoryzae]
ATGCAGATCAAGTTTGATGACAACGCATGGGAGGATTACCTCTACTGGCAGCAGAGCAGCAAGCCTACCCTCAAGCGCAT
CAACGCTCTGATCAAGGACATCCAGCGCAACCCGTTTGAGGGGATCGGCAAGCCTGAGCCGCTTAAGCACCAGTTTGCTG
GCTTCTGGTCGCGTCGCATCGATGAGGAGCATCGGCTGGTCTACGCTGTCCAGAGCAACGTTCTGACCATCTTGCAGTGC
CGCTACCACTACTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9740.92 Da
• Isoelectric Point: 5.6293

>AT110859 WP_019101444.1 NZ_CP031968:1252195-1252458 [Chromobacterium rhizoryzae]
MKALTYSHTRQHLAEVMRQVNEDRAPVIVTTQRGEPVVIMSLADYNALEETAYLTRSPENAKRLADAAARFHSGAAKERT
LLEDEGE

Nucleotide

• Length: 264 bp

>AT110859 NZ_CP031968:1252195-1252458 [Chromobacterium rhizoryzae]
ATGAAAGCGCTTACCTACAGCCATACCCGCCAGCACCTGGCCGAAGTCATGCGTCAAGTGAACGAAGACCGGGCGCCGGT
GATCGTCACCACCCAGCGCGGTGAACCGGTGGTGATCATGTCGCTGGCCGACTACAACGCGCTGGAAGAAACCGCCTACC
TGACGCGCTCCCCTGAAAATGCCAAGCGTCTGGCCGATGCGGCGGCAAGGTTTCACAGCGGGGCGGCCAAAGAGAGAACG
CTTCTCGAAGACGAGGGCGAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A2T5NK26