Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataT-tacA/DUF1778(antitoxin)
Location 25247..26046 Replicon chromosome
Accession NZ_CP031941
Organism Nostoc sphaeroides strain Kutzing En

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag D1367_RS00170 Protein ID WP_181985005.1
Coordinates 25537..26046 (+) Length 170 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag D1367_RS00165 Protein ID WP_118161638.1
Coordinates 25247..25537 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1367_RS00145 21778..23416 - 1639 Protein_26 hypothetical protein -
D1367_RS00150 23745..24101 + 357 WP_118161636.1 iron-sulfur cluster assembly accessory protein -
D1367_RS00155 24184..24606 + 423 WP_118161637.1 hypothetical protein -
D1367_RS00160 24762..25007 + 246 WP_109009489.1 hypothetical protein -
D1367_RS00165 25247..25537 + 291 WP_118161638.1 DUF1778 domain-containing protein Antitoxin
D1367_RS00170 25537..26046 + 510 WP_181985005.1 GNAT family N-acetyltransferase Toxin
D1367_RS00180 26651..27571 - 921 WP_118161641.1 TIGR01777 family oxidoreductase -
D1367_RS00185 27749..28096 + 348 WP_118161642.1 hypothetical protein -
D1367_RS00190 28169..28666 - 498 WP_118161643.1 FHA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(46-148)

Antitoxin

Vibrio phage ICP1, Orf50

(12-96)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 18852.02 Da        Isoelectric Point: 9.1361

>T110845 WP_181985005.1 NZ_CP031941:25537-26046 [Nostoc sphaeroides]
MIEQTKTINAPQPLTHEHDVLEFKSKSEALNNWLKEKALKNERDTARTFVVTVENQVIGYYCLATGSVTHLVAVSKAKRN
APDPIPCMLIARLAVDTKWEGQGIGSGLLKDAIIRILSVSQIAGVRCILVHAKDEEAKRFYLKRGFQPSPIEPLTLMMTL
KDIRASIID

Download         Length: 510 bp

>T110845 NZ_CP031941:25537-26046 [Nostoc sphaeroides]
ATGATAGAACAAACAAAAACTATTAATGCTCCTCAGCCACTTACTCATGAGCATGATGTATTAGAGTTTAAATCTAAATC
AGAAGCTTTGAATAACTGGCTGAAGGAGAAAGCTTTGAAAAATGAGAGGGATACGGCTAGAACTTTTGTGGTAACTGTTG
AAAATCAAGTAATAGGCTATTACTGTTTAGCAACCGGATCTGTAACTCATTTAGTAGCTGTTAGCAAAGCTAAACGGAAC
GCACCAGACCCTATACCGTGTATGCTTATTGCTAGACTAGCAGTCGATACCAAATGGGAAGGACAGGGTATAGGGTCTGG
CTTATTAAAAGATGCTATTATTCGTATTTTATCAGTATCCCAAATAGCAGGTGTTAGATGTATTTTGGTTCACGCTAAAG
ATGAAGAAGCCAAAAGATTTTATTTAAAACGTGGGTTTCAACCATCACCAATAGAACCATTAACACTGATGATGACTTTA
AAAGATATTCGAGCAAGCATTATAGATTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11135.78 Da        Isoelectric Point: 5.2067

>AT110845 WP_118161638.1 NZ_CP031941:25247-25537 [Nostoc sphaeroides]
MLARSKMDNLGRNQVINIRVQEQQRDLIDNAASILGKSRSDFMLEVACREAEKVICDKTFFALNEEKYQEFLTMLDSPPK
ANEEIRKLLTTKSPWD

Download         Length: 291 bp

>AT110845 NZ_CP031941:25247-25537 [Nostoc sphaeroides]
ATGCTTGCCCGTTCTAAAATGGATAACCTTGGCCGTAACCAAGTAATTAATATTAGAGTTCAAGAACAACAACGGGATTT
AATTGATAATGCCGCTTCGATTCTTGGTAAGAGCCGTTCTGACTTTATGTTAGAGGTAGCCTGCCGAGAAGCTGAAAAAG
TCATCTGTGACAAAACTTTCTTCGCGTTAAACGAGGAAAAATATCAAGAATTCCTTACTATGTTGGACTCACCACCTAAA
GCGAATGAAGAAATTCGTAAATTATTAACGACTAAATCGCCTTGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References