Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2342027..2342261 Replicon chromosome
Accession NZ_CP031922
Organism Escherichia coli O26:H11 strain FWSEC0001

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2342157..2342260 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2342027..2342261 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9S25_RS11950 2338582..2339244 - 663 WP_000944256.1 exodeoxyribonuclease X -
B9S25_RS11955 2339268..2339924 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
B9S25_RS11960 2340026..2340256 - 231 WP_000916763.1 DNA polymerase III subunit theta -
B9S25_RS11965 2340395..2340769 + 375 WP_000204699.1 CopC domain-containing protein YobA -
B9S25_RS11970 2340773..2341645 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
B9S25_RS11975 2341658..2341999 + 342 WP_000976492.1 YebY family protein -
- 2342027..2342261 - 235 - - Antitoxin
- 2342157..2342260 + 104 - - Toxin
B9S25_RS11980 2342392..2343468 - 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
B9S25_RS11985 2343434..2343715 - 282 WP_001443927.1 excisionase -
B9S25_RS11990 2343822..2344010 - 189 WP_001356607.1 DUF1187 family protein -
- 2343826..2344004 + 179 NuclAT_1 - -
- 2343826..2344004 + 179 NuclAT_1 - -
- 2343826..2344004 + 179 NuclAT_1 - -
- 2343826..2344004 + 179 NuclAT_1 - -
B9S25_RS11995 2344003..2344197 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
B9S25_RS12000 2344254..2345063 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T110790 NZ_CP031922:2342157-2342260 [Escherichia coli O26:H11]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT110790 NZ_CP031922:c2342261-2342027 [Escherichia coli O26:H11]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References