Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2352639..2352907 | Replicon | chromosome |
| Accession | NZ_CP031919 | ||
| Organism | Escherichia coli O145:NM strain FWSEC0002 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2352766..2352869 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2352639..2352907 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CCU01_RS12030 | 2349192..2349854 | - | 663 | WP_000944252.1 | exodeoxyribonuclease X | - |
| CCU01_RS12035 | 2349878..2350534 | - | 657 | WP_000011656.1 | carbon-nitrogen hydrolase family protein | - |
| CCU01_RS12040 | 2350636..2350866 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| CCU01_RS12045 | 2351005..2351379 | + | 375 | WP_000168738.1 | CopC domain-containing protein YobA | - |
| CCU01_RS12050 | 2351383..2352255 | + | 873 | WP_000879330.1 | copper homeostasis membrane protein CopD | - |
| CCU01_RS12055 | 2352268..2352609 | + | 342 | WP_000976475.1 | YebY family protein | - |
| - | 2352639..2352907 | - | 269 | - | - | Antitoxin |
| - | 2352766..2352869 | + | 104 | - | - | Toxin |
| CCU01_RS12060 | 2353004..2353660 | + | 657 | WP_000812714.1 | protein-serine/threonine phosphatase | - |
| CCU01_RS12065 | 2353661..2353852 | - | 192 | WP_001313035.1 | YebW family protein | - |
| CCU01_RS12070 | 2353957..2354193 | - | 237 | WP_001295499.1 | DUF1480 family protein | - |
| CCU01_RS12075 | 2354311..2355750 | - | 1440 | WP_024221588.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | stxA / stxB / nleC | 2276199..2358463 | 82264 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T110766 NZ_CP031919:2352766-2352869 [Escherichia coli O145:NM]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 269 bp
>AT110766 NZ_CP031919:c2352907-2352639 [Escherichia coli O145:NM]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
