Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3164691..3164925 Replicon chromosome
Accession NZ_CP031916
Organism Escherichia coli O45:H2 strain FWSEC0003

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3164692..3164795 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3164691..3164925 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCU02_RS16190 3161889..3162698 + 810 WP_000166311.1 recombination protein RecT -
CCU02_RS16195 3162755..3162949 + 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
CCU02_RS16200 3162942..3163130 + 189 WP_001356607.1 DUF1187 family protein -
- 3162948..3163126 - 179 NuclAT_1 - -
- 3162948..3163126 - 179 NuclAT_1 - -
- 3162948..3163126 - 179 NuclAT_1 - -
- 3162948..3163126 - 179 NuclAT_1 - -
CCU02_RS16205 3163237..3163518 + 282 WP_001311878.1 excisionase -
CCU02_RS16210 3163484..3164560 + 1077 WP_001189081.1 phage integrase Arm DNA-binding domain-containing protein -
- 3164691..3164925 + 235 - - Antitoxin
- 3164692..3164795 - 104 - - Toxin
CCU02_RS16215 3164953..3165294 - 342 WP_000976472.1 YebY family protein -
CCU02_RS16220 3165307..3166179 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
CCU02_RS16225 3166183..3166557 - 375 WP_000204700.1 CopC domain-containing protein YobA -
CCU02_RS16230 3166696..3166926 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CCU02_RS16235 3167028..3167684 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CCU02_RS16240 3167708..3168370 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T110738 NZ_CP031916:c3164795-3164692 [Escherichia coli O45:H2]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTACTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT110738 NZ_CP031916:3164691-3164925 [Escherichia coli O45:H2]
TAAAAAAAGACCGAGTACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References