Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2024788..2025059 Replicon chromosome
Accession NZ_CP031906
Organism Escherichia coli O91:H21 strain FWSEC0008

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2024918..2025021 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2024788..2025059 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAX06_RS09830 2021343..2022005 - 663 WP_000944256.1 exodeoxyribonuclease X -
CAX06_RS09835 2022029..2022685 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CAX06_RS09840 2022787..2023017 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CAX06_RS09845 2023156..2023530 + 375 WP_000204699.1 CopC domain-containing protein YobA -
CAX06_RS09850 2023534..2024406 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
CAX06_RS09855 2024419..2024760 + 342 WP_000976492.1 YebY family protein -
- 2024788..2025059 - 272 - - Antitoxin
- 2024918..2025021 + 104 - - Toxin
CAX06_RS09860 2025156..2025812 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
CAX06_RS09865 2025813..2026004 - 192 WP_001296140.1 YebW family protein -
CAX06_RS09870 2026109..2026345 - 237 WP_001295499.1 DUF1480 family protein -
CAX06_RS09875 2026463..2027902 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T110585 NZ_CP031906:2024918-2025021 [Escherichia coli O91:H21]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT110585 NZ_CP031906:c2025059-2024788 [Escherichia coli O91:H21]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References