Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2228877..2229148 Replicon chromosome
Accession NZ_CP031902
Organism Escherichia coli O104:H4 strain FWSEC0009

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2229007..2229110 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2228877..2229148 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C8200_RS11175 2225432..2226094 - 663 WP_000944256.1 exodeoxyribonuclease X -
C8200_RS11180 2226118..2226774 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C8200_RS11185 2226876..2227106 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C8200_RS11190 2227245..2227619 + 375 WP_000204699.1 CopC domain-containing protein YobA -
C8200_RS11195 2227623..2228495 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C8200_RS11200 2228508..2228849 + 342 WP_000976472.1 YebY family protein -
- 2228877..2229148 - 272 - - Antitoxin
- 2229007..2229110 + 104 - - Toxin
C8200_RS11205 2229245..2229901 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
C8200_RS11210 2229902..2230093 - 192 WP_001296140.1 YebW family protein -
C8200_RS11215 2230198..2230434 - 237 WP_001295499.1 DUF1480 family protein -
C8200_RS11220 2230552..2231991 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T110558 NZ_CP031902:2229007-2229110 [Escherichia coli O104:H4]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT110558 NZ_CP031902:c2229148-2228877 [Escherichia coli O104:H4]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References