Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1971201..1971346 Replicon chromosome
Accession NZ_CP031885
Organism Klebsiella pneumoniae strain WCHKP095845

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1971237..1971339 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1971201..1971346 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BT110_RS11435 1966331..1968391 + 2061 WP_004151449.1 oligopeptidase B -
BT110_RS11440 1968395..1969054 - 660 WP_021440386.1 exodeoxyribonuclease X -
BT110_RS11445 1969133..1969363 - 231 WP_002911406.1 DNA polymerase III subunit theta -
BT110_RS11450 1969476..1969850 + 375 WP_004151448.1 CopC domain-containing protein YobA -
BT110_RS11455 1969854..1970723 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
BT110_RS11460 1970740..1971078 + 339 WP_002911404.1 YebY family protein -
- 1971201..1971346 - 146 - - Antitoxin
- 1971237..1971339 + 103 - - Toxin
BT110_RS28035 1971715..1971858 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
BT110_RS11470 1971963..1972931 - 969 WP_004151446.1 VirK/YbjX family protein -
BT110_RS11475 1973088..1973741 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
BT110_RS11480 1973738..1973929 - 192 WP_002911395.1 YebW family protein -
BT110_RS11485 1974027..1974266 - 240 WP_002911393.1 YebV family protein -
BT110_RS11490 1974382..1975815 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1906400..1978572 72172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T110471 NZ_CP031885:1971237-1971339 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT110471 NZ_CP031885:c1971346-1971201 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References