Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1860836..1860981 Replicon chromosome
Accession NZ_CP031849
Organism Klebsiella pneumoniae strain 121

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1860872..1860974 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1860836..1860981 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1Y71_RS09355 1855966..1858026 + 2061 WP_004151449.1 oligopeptidase B -
D1Y71_RS09360 1858030..1858689 - 660 WP_002911407.1 exodeoxyribonuclease X -
D1Y71_RS09365 1858768..1858998 - 231 WP_002911406.1 DNA polymerase III subunit theta -
D1Y71_RS09370 1859111..1859485 + 375 WP_004151448.1 CopC domain-containing protein YobA -
D1Y71_RS09375 1859489..1860358 + 870 WP_071443872.1 copper homeostasis membrane protein CopD -
D1Y71_RS09380 1860375..1860713 + 339 WP_016529031.1 YebY family protein -
- 1860836..1860981 - 146 - - Antitoxin
- 1860872..1860974 + 103 - - Toxin
D1Y71_RS28635 1861350..1861493 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
D1Y71_RS09390 1861598..1862566 - 969 WP_004151446.1 VirK/YbjX family protein -
D1Y71_RS09395 1862723..1863376 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
D1Y71_RS09400 1863373..1863564 - 192 WP_002911395.1 YebW family protein -
D1Y71_RS09405 1863662..1863901 - 240 WP_002911393.1 YebV family protein -
D1Y71_RS09410 1864017..1865450 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T110353 NZ_CP031849:1860872-1860974 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT110353 NZ_CP031849:c1860981-1860836 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References