Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 2439924..2440504 Replicon chromosome
Accession NZ_CP031848
Organism Marinobacter sp. Arc7-DN-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D0851_RS11465 Protein ID WP_117618772.1
Coordinates 2440202..2440504 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D0851_RS11460 Protein ID WP_117618771.1
Coordinates 2439924..2440205 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0851_RS11410 2435794..2436036 + 243 WP_058092928.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
D0851_RS11415 2436033..2436296 + 264 WP_117618763.1 Txe/YoeB family addiction module toxin -
D0851_RS11420 2436426..2436716 + 291 WP_117618764.1 type II toxin-antitoxin system RelE/ParE family toxin -
D0851_RS11425 2436729..2437016 + 288 WP_205422336.1 HigA family addiction module antidote protein -
D0851_RS11430 2437118..2437408 - 291 WP_117618766.1 type II toxin-antitoxin system RelE/ParE family toxin -
D0851_RS11435 2437401..2437622 - 222 WP_117618767.1 hypothetical protein -
D0851_RS11440 2437811..2438146 + 336 WP_117618768.1 hypothetical protein -
D0851_RS11445 2438148..2438645 + 498 WP_117618769.1 hypothetical protein -
D0851_RS11450 2438645..2438854 - 210 Protein_2221 transposase zinc-binding domain-containing protein -
D0851_RS11455 2438851..2439741 - 891 WP_117618770.1 site-specific integrase -
D0851_RS11460 2439924..2440205 + 282 WP_117618771.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
D0851_RS11465 2440202..2440504 + 303 WP_117618772.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D0851_RS11475 2441649..2442146 + 498 WP_117618773.1 hypothetical protein -
D0851_RS11480 2442313..2442537 + 225 WP_117618774.1 addiction module protein -
D0851_RS11485 2442534..2442827 + 294 WP_117618775.1 type II toxin-antitoxin system RelE/ParE family toxin -
D0851_RS11490 2443261..2444220 + 960 WP_117618776.1 reverse transcriptase N-terminal domain-containing protein -
D0851_RS11495 2444217..2444408 + 192 WP_117618777.1 hypothetical protein -
D0851_RS11500 2444526..2444852 - 327 WP_117618778.1 CcdB family protein -
D0851_RS11505 2444852..2445097 - 246 WP_071267913.1 type II toxin-antitoxin system CcdA family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2101406..2499414 398008


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11500.13 Da        Isoelectric Point: 4.5533

>T110345 WP_117618772.1 NZ_CP031848:2440202-2440504 [Marinobacter sp. Arc7-DN-1]
MKIVWSPLALERVEDTARYIAEDNPDTAIRWVDDLFATVERLADFPKSGRMVPEVGSPRIRELIFGAYRVIYSVKDQVDI
LTVRRSSQLLRMSELGDDET

Download         Length: 303 bp

>T110345 NZ_CP031848:2440202-2440504 [Marinobacter sp. Arc7-DN-1]
ATGAAGATTGTTTGGTCCCCGCTTGCGCTGGAGCGCGTCGAGGATACCGCTCGGTATATTGCAGAAGACAACCCAGATAC
TGCGATACGGTGGGTTGATGATTTATTTGCCACAGTAGAGCGGTTAGCTGATTTCCCTAAAAGTGGACGCATGGTTCCTG
AGGTGGGGTCACCTCGCATCAGGGAGCTGATATTTGGAGCGTACCGGGTTATTTACAGCGTCAAAGATCAGGTTGATATT
TTGACTGTGCGTCGCAGTAGCCAGTTATTGCGGATGTCTGAACTCGGTGATGACGAAACATAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10603.05 Da        Isoelectric Point: 5.6730

>AT110345 WP_117618771.1 NZ_CP031848:2439924-2440205 [Marinobacter sp. Arc7-DN-1]
MSRVRVDEDIRPLSEFRAGVATFVKQLHENRRPMVLTQRGRGVAVLVDVHEYEKMQERLEILEEVYKAEEQITSGDGIAH
EDAKARVLSGLAQ

Download         Length: 282 bp

>AT110345 NZ_CP031848:2439924-2440205 [Marinobacter sp. Arc7-DN-1]
ATGTCAAGGGTTCGTGTAGATGAAGATATCCGTCCTCTGTCTGAATTCCGGGCAGGGGTAGCCACATTTGTAAAGCAGCT
CCATGAAAACCGTCGTCCTATGGTGCTGACACAAAGAGGTCGTGGCGTTGCCGTACTGGTGGATGTTCACGAGTACGAGA
AGATGCAAGAACGTCTGGAAATACTAGAAGAGGTGTATAAGGCGGAAGAACAGATAACTTCCGGTGATGGTATTGCGCAT
GAAGACGCGAAGGCTCGGGTTTTAAGCGGGCTGGCCCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References