Detailed information of TA system TA110338

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1142619..1143150
• Replicon: chromosome
• Accession: NZ_CP031848
• Organism: Marinobacter sp. Arc7-DN-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: D0851_RS05295
• Protein ID: WP_117617686.1
• Coordinates: 1142619..1142912 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: D0851_RS05300
• Protein ID: WP_117617687.1
• Coordinates: 1142902..1143150 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D0851_RS05280	1139293..1140504	+	1212	WP_117617684.1	hypothetical protein	-
D0851_RS05285	1141058..1142320	-	1263	WP_117617685.1	Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB	-
D0851_RS05290	1142338..1142591	-	254	Protein_1014	DUF2442 domain-containing protein	-
D0851_RS05295	1142619..1142912	-	294	WP_117617686.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
D0851_RS05300	1142902..1143150	-	249	WP_117617687.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
D0851_RS05305	1143243..1144727	-	1485	WP_117620291.1	MBL fold metallo-hydrolase	-
D0851_RS05310	1145083..1145763	-	681	WP_205422272.1	Fic family protein	-
D0851_RS05315	1146072..1146200	-	129	Protein_1019	transposase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (8-85)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11368.18 Da
• Isoelectric Point: 9.9379

>T110338 WP_117617686.1 NZ_CP031848:c1142912-1142619 [Marinobacter sp. Arc7-DN-1]
MSSEYQLAFKRSALKEWKKLAEPVKKQFKKKLEERLDMPRVASDALSGFENYYKIKLRSVGYRLVYEVQDETVTVTVIAV
GTCERADVYRKAKDRLE

Nucleotide

• Length: 294 bp

>T110338 NZ_CP031848:c1142912-1142619 [Marinobacter sp. Arc7-DN-1]
ATGAGCTCTGAGTACCAGCTTGCTTTCAAGAGGTCTGCGCTAAAAGAATGGAAAAAGCTGGCTGAGCCCGTCAAGAAACA
GTTCAAAAAGAAACTTGAAGAGCGGCTTGATATGCCGCGCGTTGCCTCGGATGCCCTCTCAGGGTTTGAAAATTATTACA
AGATCAAGCTGCGAAGTGTCGGATACAGGCTTGTTTACGAAGTTCAGGATGAGACGGTAACGGTTACTGTTATCGCCGTA
GGGACATGTGAGAGAGCCGATGTATACAGAAAGGCAAAAGATCGTCTCGAATGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9156.39 Da
• Isoelectric Point: 4.5556

>AT110338 WP_117617687.1 NZ_CP031848:c1143150-1142902 [Marinobacter sp. Arc7-DN-1]
MTSPIYSEVTASVSELKKNPMATVRDGGGFPVAVLNRNKPAFYCVPADVYEAMLERLDDQNLADIVRERRSEPSVRVDLN
EL

Nucleotide

• Length: 249 bp

>AT110338 NZ_CP031848:c1143150-1142902 [Marinobacter sp. Arc7-DN-1]
ATGACTAGCCCAATCTATTCAGAGGTTACTGCCAGCGTGTCAGAGCTTAAAAAGAACCCGATGGCGACAGTTCGTGATGG
GGGTGGTTTCCCTGTGGCTGTGCTCAACCGGAACAAGCCTGCCTTTTATTGCGTGCCGGCTGATGTGTATGAGGCAATGT
TGGAGCGACTGGATGACCAGAATCTTGCTGATATTGTGCGAGAGCGCCGCTCGGAGCCGAGCGTGCGGGTCGATCTGAAT
GAGCTCTGA