Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 758087..758634 Replicon chromosome
Accession NZ_CP031848
Organism Marinobacter sp. Arc7-DN-1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag D0851_RS03525 Protein ID WP_117617386.1
Coordinates 758335..758634 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag D0851_RS03520 Protein ID WP_117617385.1
Coordinates 758087..758335 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0851_RS03495 753609..754709 - 1101 WP_162893683.1 efflux RND transporter periplasmic adaptor subunit -
D0851_RS03500 754702..756003 - 1302 WP_162893684.1 TolC family protein -
D0851_RS20150 756142..756534 - 393 WP_162893685.1 hypothetical protein -
D0851_RS03510 757043..757345 + 303 WP_117617383.1 type II toxin-antitoxin system HigB family toxin -
D0851_RS03515 757363..757731 + 369 WP_117617384.1 transcriptional regulator -
D0851_RS03520 758087..758335 + 249 WP_117617385.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
D0851_RS03525 758335..758634 + 300 WP_117617386.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D0851_RS03530 758919..759161 + 243 WP_117617387.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
D0851_RS03535 759182..759571 + 390 WP_205422313.1 PIN domain-containing protein -
D0851_RS03540 759739..761316 - 1578 WP_117617389.1 glutamine-hydrolyzing GMP synthase -
D0851_RS03545 761380..762843 - 1464 WP_117617390.1 IMP dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(1-70)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11647.31 Da        Isoelectric Point: 9.2914

>T110336 WP_117617386.1 NZ_CP031848:758335-758634 [Marinobacter sp. Arc7-DN-1]
MPGFRVTPRAQDDLKNIGRYTEQHWGKRQRNNYLKALEKRFGWLAENPRLGKHRLDVAEGYYSFPQGEHVVFYLIGEKGI
DIIGVPHKEMDIITYFLPD

Download         Length: 300 bp

>T110336 NZ_CP031848:758335-758634 [Marinobacter sp. Arc7-DN-1]
ATGCCCGGATTCAGAGTTACCCCGAGGGCTCAGGATGACTTAAAAAACATCGGCCGATATACAGAGCAGCACTGGGGTAA
ACGCCAACGAAATAATTACCTGAAAGCACTCGAAAAACGCTTTGGCTGGTTAGCAGAAAATCCACGGTTGGGCAAACATC
GCCTGGATGTGGCTGAAGGCTATTACAGTTTCCCTCAAGGCGAGCATGTTGTCTTCTACCTGATTGGTGAAAAAGGCATT
GATATTATCGGCGTCCCGCACAAGGAGATGGATATCATTACTTATTTTCTACCTGACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9245.30 Da        Isoelectric Point: 4.6388

>AT110336 WP_117617385.1 NZ_CP031848:758087-758335 [Marinobacter sp. Arc7-DN-1]
MATTSLSLGEHWEVYIKNEIASGRYGSASEVVRDALRSMEERKSKLDALRSHLAQGVEQARASEFIDNFKMDTLINDLDN
EV

Download         Length: 249 bp

>AT110336 NZ_CP031848:758087-758335 [Marinobacter sp. Arc7-DN-1]
ATGGCAACGACAAGTCTCAGCCTAGGTGAGCACTGGGAAGTTTACATCAAGAATGAGATTGCCAGCGGGCGTTACGGCTC
TGCCAGTGAAGTTGTCCGGGATGCCCTACGCTCAATGGAAGAGCGCAAAAGCAAACTTGACGCTTTACGAAGTCATTTGG
CGCAGGGCGTTGAACAGGCCAGAGCCAGTGAGTTCATTGATAATTTCAAAATGGACACACTGATCAACGATCTGGATAAC
GAAGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References