Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 111243..111745 Replicon chromosome
Accession NZ_CP031848
Organism Marinobacter sp. Arc7-DN-1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag D0851_RS00575 Protein ID WP_117616887.1
Coordinates 111491..111745 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D0851_RS00570 Protein ID WP_117616886.1
Coordinates 111243..111494 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0851_RS00530 106411..107235 - 825 WP_117616881.1 haloacid dehalogenase-like hydrolase -
D0851_RS00535 107365..108021 - 657 WP_117616882.1 methyltransferase domain-containing protein -
D0851_RS00540 108150..108812 - 663 WP_117616883.1 class I SAM-dependent methyltransferase -
D0851_RS00545 109103..109621 - 519 WP_117616884.1 DUF2141 domain-containing protein -
D0851_RS00555 109926..110384 - 459 WP_162893653.1 nuclear transport factor 2 family protein -
D0851_RS00560 110511..110645 + 135 Protein_103 transposase -
D0851_RS00565 110728..110844 + 117 Protein_104 IS110 family transposase -
D0851_RS00570 111243..111494 + 252 WP_117616886.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
D0851_RS00575 111491..111745 + 255 WP_117616887.1 Txe/YoeB family addiction module toxin Toxin
D0851_RS00580 112012..112710 - 699 WP_117616888.1 NrdJb -
D0851_RS00585 112738..114876 - 2139 WP_117616889.1 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase -
D0851_RS00590 115324..116133 + 810 WP_117616890.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10198.77 Da        Isoelectric Point: 9.9936

>T110334 WP_117616887.1 NZ_CP031848:111491-111745 [Marinobacter sp. Arc7-DN-1]
MKLIFSENAWEDYLYWQKTDKKILNRINKLIKETKRGPFEGVGKPEPLKHSLAGYWSRRINEEHRIVYKVTDDALFIAQL
RYHY

Download         Length: 255 bp

>T110334 NZ_CP031848:111491-111745 [Marinobacter sp. Arc7-DN-1]
ATGAAACTCATCTTCTCCGAGAACGCCTGGGAAGACTATCTGTACTGGCAGAAAACTGACAAAAAGATCCTTAACCGAAT
CAACAAGCTGATCAAAGAAACCAAGCGCGGACCATTTGAAGGTGTCGGTAAACCAGAACCGCTCAAGCATAGCCTCGCTG
GTTACTGGTCCCGCCGAATTAACGAAGAACACCGCATCGTTTACAAGGTCACGGATGATGCTTTGTTCATTGCCCAGCTG
CGGTACCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9299.52 Da        Isoelectric Point: 4.4750

>AT110334 WP_117616886.1 NZ_CP031848:111243-111494 [Marinobacter sp. Arc7-DN-1]
MDAISYTAARTNLAKTMEQVCEDHSPVIITRSKSQSVVMISLEDYEALQETAYLLRTPKNARRLLESVAELEQGGGQEKE
LLE

Download         Length: 252 bp

>AT110334 NZ_CP031848:111243-111494 [Marinobacter sp. Arc7-DN-1]
ATGGATGCCATTAGCTACACAGCCGCTAGAACCAATCTAGCAAAAACCATGGAGCAGGTCTGTGAAGACCATTCTCCTGT
GATCATCACCCGGAGCAAGTCGCAATCCGTGGTCATGATCTCTCTTGAGGACTATGAGGCGTTGCAAGAGACCGCATACC
TCCTGCGCACACCAAAGAACGCCCGTCGTTTGCTGGAATCGGTTGCCGAACTTGAGCAAGGCGGTGGTCAGGAAAAGGAA
CTTCTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References