Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 20550..21039 Replicon chromosome
Accession NZ_CP031848
Organism Marinobacter sp. Arc7-DN-1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag D0851_RS00140 Protein ID WP_117616815.1
Coordinates 20550..20813 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag D0851_RS00145 Protein ID WP_117616816.1
Coordinates 20803..21039 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0851_RS00095 15792..16031 - 240 WP_012140687.1 type II toxin-antitoxin system ParD family antitoxin -
D0851_RS00100 16203..16424 + 222 WP_117620215.1 addiction module protein -
D0851_RS00105 16424..16735 + 312 WP_117616810.1 type II toxin-antitoxin system RelE/ParE family toxin -
D0851_RS00110 16787..17638 + 852 WP_117616811.1 site-specific integrase -
D0851_RS00115 17638..18759 + 1122 WP_117620216.1 IS91 family transposase -
D0851_RS00120 19076..19390 - 315 WP_117616812.1 type II toxin-antitoxin system RelE/ParE family toxin -
D0851_RS00125 19393..19629 - 237 WP_117616813.1 addiction module protein -
D0851_RS00135 19882..20394 + 513 Protein_22 hypothetical protein -
D0851_RS00140 20550..20813 + 264 WP_117616815.1 BrnT family toxin Toxin
D0851_RS00145 20803..21039 + 237 WP_117616816.1 CopG family transcriptional regulator Antitoxin
D0851_RS00150 21087..21365 + 279 WP_117616817.1 toxin -
D0851_RS00155 21362..21634 + 273 WP_117616818.1 antitoxin -
D0851_RS00160 21869..22270 - 402 WP_117616819.1 PIN domain nuclease -
D0851_RS00165 22267..22461 - 195 WP_117616820.1 type II toxin-antitoxin system VapB family antitoxin -
D0851_RS00170 22599..22871 - 273 WP_117616821.1 BrnA antitoxin family protein -
D0851_RS00175 22846..23157 - 312 WP_117616822.1 BrnT family toxin -
D0851_RS00180 23665..24330 - 666 WP_117616823.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10240.60 Da        Isoelectric Point: 4.9409

>T110333 WP_117616815.1 NZ_CP031848:20550-20813 [Marinobacter sp. Arc7-DN-1]
MDEFELDETKSQANLEKHDIDFEAAQKLWEDPYLLEIRAKSEDEPRFLLIGNIGGKHWSAVVTYRVGCIRLISVRRSRKK
EVELYES

Download         Length: 264 bp

>T110333 NZ_CP031848:20550-20813 [Marinobacter sp. Arc7-DN-1]
ATGGATGAGTTTGAGCTCGACGAAACCAAAAGCCAGGCCAATCTGGAAAAGCACGATATTGATTTCGAAGCGGCCCAAAA
ACTGTGGGAAGATCCGTACCTGCTGGAAATCCGTGCAAAATCAGAGGATGAGCCAAGGTTCTTGCTGATCGGCAATATTG
GCGGAAAGCACTGGTCGGCTGTCGTCACTTACAGGGTAGGCTGTATTCGCCTGATTTCAGTCAGGCGCTCTCGCAAGAAG
GAGGTTGAGCTCTATGAAAGCTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9088.27 Da        Isoelectric Point: 5.1832

>AT110333 WP_117616816.1 NZ_CP031848:20803-21039 [Marinobacter sp. Arc7-DN-1]
MKAKDFDKKFEEGQEDIVDDLDLSSARRVNQDQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLRAETANK

Download         Length: 237 bp

>AT110333 NZ_CP031848:20803-21039 [Marinobacter sp. Arc7-DN-1]
ATGAAAGCTAAAGACTTCGATAAAAAATTTGAGGAAGGTCAGGAAGATATCGTTGATGATCTTGATCTTTCTTCGGCTCG
CCGCGTCAATCAGGACCAAAAGCGAATCAACGTTGATTTTCCGGCTTGGGTTGTCGAGTCGCTGGACCGTGAGGCAGCGC
GCATTGGTGTTACCCGCCAATCGATCATAAAGGTGTGGCTGGTTGAGCGCCTTCGTGCAGAAACTGCTAACAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References