Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) paaR-paaA-parE/ParE(toxin)
Location 1774891..1775366 Replicon chromosome
Accession NZ_CP031844
Organism Bartonella krasnovii strain OE 1-1

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag D1092_RS07655 Protein ID WP_210247575.1
Coordinates 1774891..1775181 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag D1092_RS07660 Protein ID WP_120121238.1
Coordinates 1775178..1775366 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1092_RS07620 1769928..1770187 - 260 Protein_1426 DUF1465 family protein -
D1092_RS07625 1770214..1770473 - 260 Protein_1427 DUF1465 family protein -
D1092_RS07630 1770500..1771018 - 519 WP_120121229.1 DUF1465 family protein -
D1092_RS07635 1771219..1772361 - 1143 WP_120121231.1 OpgC domain-containing protein -
D1092_RS07640 1772637..1773299 + 663 WP_120121233.1 thiamine phosphate synthase -
D1092_RS07645 1773902..1774303 + 402 WP_120122708.1 helix-turn-helix domain-containing protein -
D1092_RS07650 1774310..1774531 + 222 WP_148255698.1 hypothetical protein -
D1092_RS07655 1774891..1775181 - 291 WP_210247575.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
D1092_RS07660 1775178..1775366 - 189 WP_120121238.1 antitoxin Antitoxin
D1092_RS07665 1775870..1776238 + 369 WP_120121240.1 helix-turn-helix domain-containing protein -
D1092_RS09570 1776555..1776752 + 198 WP_167309321.1 hypothetical protein -
D1092_RS07680 1778177..1779220 + 1044 WP_120121242.1 sel1 repeat family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11197.12 Da        Isoelectric Point: 10.1866

>T110324 WP_210247575.1 NZ_CP031844:c1775181-1774891 [Bartonella krasnovii]
VMLPVVWLSSARDDLRQILTYIARENPSAARRMKRFLETSVLPLAEHPYLYRQSERILGLREIIAHPNYLILYRVAANQI
EIVAVVHARREFPTSL

Download         Length: 291 bp

>T110324 NZ_CP031844:c1775181-1774891 [Bartonella krasnovii]
GTGATGCTTCCGGTTGTTTGGTTGTCTTCGGCTCGCGATGATTTGCGTCAGATTTTAACTTACATTGCTCGTGAAAATCC
ATCCGCTGCACGCCGAATGAAAAGGTTTTTGGAAACATCTGTACTGCCATTGGCTGAACATCCATATCTGTACAGACAGA
GTGAGAGGATATTAGGGTTACGGGAAATTATAGCACATCCAAATTACCTTATATTGTATCGAGTAGCTGCAAATCAGATC
GAAATTGTAGCTGTCGTACATGCCCGACGTGAATTCCCTACCTCTCTTTAA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7068.01 Da        Isoelectric Point: 4.3167

>AT110324 WP_120121238.1 NZ_CP031844:c1775366-1775178 [Bartonella krasnovii]
MKNTLSPFISEFETIEQESSHTAWLRDKVAISLANLSPPIPHDEVMAEMDVIISQLENEQKK

Download         Length: 189 bp

>AT110324 NZ_CP031844:c1775366-1775178 [Bartonella krasnovii]
ATGAAAAACACCCTTTCTCCGTTCATTTCAGAGTTCGAAACTATTGAACAGGAAAGCAGCCACACGGCGTGGTTGCGCGA
TAAGGTCGCGATAAGTCTTGCAAACCTATCTCCTCCTATTCCGCATGATGAGGTCATGGCTGAAATGGACGTTATAATCA
GTCAGCTTGAAAATGAACAGAAAAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References