110311

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FicTA/Fic(toxin)
Location 34757..35525 Replicon chromosome
Accession NZ_CP031843
Organism Bartonella kosoyi strain Tel Aviv

Toxin (Protein)


Gene name VbhT Uniprot ID -
Locus tag D1093_RS00210 Protein ID WP_120099868.1
Coordinates 34757..35350 (-) Length 198 a.a.

Antitoxin (Protein)


Gene name VbhA Uniprot ID -
Locus tag D1093_RS00215 Protein ID WP_120099869.1
Coordinates 35337..35525 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1093_RS00165 31256..32008 + 753 WP_120099859.1 type IV secretion protein VblB5 -
D1093_RS00170 32032..32367 + 336 WP_120099860.1 EexN family lipoprotein -
D1093_RS00175 32406..32786 + 381 WP_120099861.1 EexN family lipoprotein -
D1093_RS00180 32789..33172 + 384 WP_120099862.1 EexN family lipoprotein -
D1093_RS00190 33456..33746 + 291 WP_120099864.1 EexN family lipoprotein -
D1093_RS00200 34040..34456 + 417 WP_120099866.1 EexN family lipoprotein -
D1093_RS00205 34503..34778 + 276 WP_120099867.1 type IV secretion system protein -
D1093_RS00210 34757..35350 - 594 WP_120099868.1 Fic family protein Toxin
D1093_RS00215 35337..35525 - 189 WP_120099869.1 antitoxin VbhA family protein Antitoxin
D1093_RS00220 35726..35971 - 246 WP_120099870.1 HigA family addiction module antidote protein -
D1093_RS00230 36372..36566 - 195 WP_150222231.1 hypothetical protein -
D1093_RS00235 36770..38131 - 1362 WP_120099872.1 phosphoglucosamine mutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(55-152)

Antitoxin

Antitoxin VbhA

(10-53)


Sequences

Toxin        


Download         Length: 198 a.a.        Molecular weight: 22657.49 Da        Isoelectric Point: 6.9253

>T110311 WP_120099868.1 NZ_CP031843:c35350-34757 [Bartonella kosoyi]
VEKYKGGGDPYTDPKTGVMYNRFEIQDKTALERVESTFSYVRSFELMRAATGGKFDLSHMKEIHRKLFGDVYEWAGEIRS
VDIAKGNSMFAYHHQIESYTPKITQQLAKEQYLRGLDADEFSQRAGYYMGELNALHPFREGNGRTLREFMGQLAREAGYN
INWDGITREEMTKASIAAHFGHSDHMSVLIRQNLNLL

Download         Length: 594 bp

>T110311 NZ_CP031843:c35350-34757 [Bartonella kosoyi]
GTGGAGAAATATAAAGGGGGCGGTGATCCTTATACTGATCCTAAAACTGGTGTGATGTATAATCGGTTTGAAATTCAGGA
TAAAACCGCACTGGAGCGTGTAGAATCTACTTTCTCTTATGTAAGGTCTTTTGAACTTATGCGTGCTGCTACGGGTGGTA
AGTTTGATCTCAGCCACATGAAAGAGATCCATAGAAAACTGTTTGGTGACGTCTATGAATGGGCGGGAGAGATCCGTTCA
GTGGATATTGCCAAAGGCAATAGTATGTTTGCTTATCATCATCAGATTGAAAGTTATACACCGAAGATTACGCAACAGCT
TGCAAAAGAACAATATCTGCGTGGTCTTGATGCAGATGAATTTAGCCAAAGAGCTGGATATTACATGGGAGAGTTGAATG
CCTTGCATCCATTTCGAGAGGGAAATGGGCGCACGTTGCGTGAATTTATGGGGCAACTTGCTCGTGAAGCTGGTTATAAT
ATCAACTGGGACGGTATCACGCGAGAGGAAATGACAAAGGCATCAATTGCAGCCCATTTTGGTCATTCTGACCATATGTC
TGTACTTATTCGTCAAAACCTCAATCTCTTATAA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7193.37 Da        Isoelectric Point: 4.8409

>AT110311 WP_120099869.1 NZ_CP031843:c35525-35337 [Bartonella kosoyi]
MLSEDEIKRRRFAAKNALASQRLEGLEPDPKVVEQMERVIIGELEISDVIKDLMERIKRGEI

Download         Length: 189 bp

>AT110311 NZ_CP031843:c35525-35337 [Bartonella kosoyi]
ATGTTGAGTGAAGACGAAATTAAGCGACGTCGCTTTGCTGCTAAAAATGCATTAGCAAGTCAACGTTTAGAGGGGTTGGA
GCCAGATCCAAAAGTCGTGGAGCAAATGGAGCGGGTTATTATAGGTGAACTTGAAATAAGTGATGTAATCAAGGATCTTA
TGGAACGGATAAAACGTGGAGAAATATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References