Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2648614..2649124 Replicon chromosome
Accession NZ_CP031842
Organism Dechloromonas sp. HYN0024

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HYN24_RS12710 Protein ID WP_117609592.1
Coordinates 2648614..2648874 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HYN24_RS12715 Protein ID WP_117609593.1
Coordinates 2648864..2649124 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYN24_RS12685 2643793..2644914 + 1122 WP_117609587.1 glutamate 5-kinase -
HYN24_RS12690 2645054..2645725 + 672 WP_117609588.1 recombinase family protein -
HYN24_RS12695 2645781..2646875 - 1095 WP_117609589.1 porin -
HYN24_RS12700 2647077..2647409 - 333 WP_117609590.1 nucleotidyltransferase domain-containing protein -
HYN24_RS12705 2647409..2648617 - 1209 WP_117609591.1 indole-3-glycerol phosphate synthase TrpC -
HYN24_RS12710 2648614..2648874 - 261 WP_117609592.1 Txe/YoeB family addiction module toxin Toxin
HYN24_RS12715 2648864..2649124 - 261 WP_117609593.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HYN24_RS12720 2649173..2650201 - 1029 WP_117609594.1 anthranilate phosphoribosyltransferase -
HYN24_RS12725 2650198..2650770 - 573 WP_117610382.1 aminodeoxychorismate/anthranilate synthase component II -
HYN24_RS12730 2651007..2651300 + 294 WP_117609595.1 ADP-ribosyl-(dinitrogen reductase) hydrolase -
HYN24_RS12735 2651290..2651625 + 336 WP_205421389.1 hypothetical protein -
HYN24_RS12740 2651771..2652781 + 1011 WP_117609597.1 glycosyltransferase family 2 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10268.73 Da        Isoelectric Point: 7.9038

>T110310 WP_117609592.1 NZ_CP031842:c2648874-2648614 [Dechloromonas sp. HYN0024]
MPIKFADLAWADYLFWQQADKATTKRIHTLIKDIQRSPFEGIGKPEPLRHNFSGFWSRRIDEEHRLVYTIDDGCLVIVQC
RYHYQS

Download         Length: 261 bp

>T110310 NZ_CP031842:c2648874-2648614 [Dechloromonas sp. HYN0024]
ATGCCGATTAAATTCGCTGATCTTGCCTGGGCGGATTACCTGTTCTGGCAACAGGCCGACAAGGCAACGACCAAGCGAAT
CCATACGCTGATCAAGGATATCCAGCGGTCTCCCTTTGAAGGCATCGGCAAGCCCGAGCCTTTGCGACATAACTTTTCCG
GTTTCTGGTCGCGACGCATTGATGAGGAACATCGCCTTGTCTACACCATCGATGATGGTTGCCTCGTAATAGTCCAGTGC
CGCTACCACTACCAATCATGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9534.73 Da        Isoelectric Point: 4.4553

>AT110310 WP_117609593.1 NZ_CP031842:c2649124-2648864 [Dechloromonas sp. HYN0024]
VDTMTYSYTRQNFANVMDRVNDDRAPLLITRQQGKPVVMMSLDDFNALEETAYLLRSPANAQRLIDAIAEVRSGGGSTKT
LPLDAD

Download         Length: 261 bp

>AT110310 NZ_CP031842:c2649124-2648864 [Dechloromonas sp. HYN0024]
GTGGATACAATGACTTACAGCTACACCCGCCAGAATTTCGCCAATGTGATGGACCGCGTCAATGATGACCGCGCGCCGCT
GCTGATTACCCGTCAGCAAGGCAAGCCGGTGGTCATGATGTCGCTTGACGATTTCAACGCCCTCGAGGAAACGGCCTATC
TGCTGCGCAGCCCGGCCAATGCCCAGCGTTTGATCGATGCCATTGCAGAGGTGCGCTCAGGTGGTGGAAGCACCAAAACC
CTCCCGCTCGATGCCGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References