Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 3303659..3304198 Replicon chromosome
Accession NZ_CP031841
Organism Breoghania sp. L-A4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag D1F64_RS15125 Protein ID WP_117413097.1
Coordinates 3303911..3304198 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag D1F64_RS15120 Protein ID WP_117413096.1
Coordinates 3303659..3303907 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1F64_RS15095 3298758..3298973 - 216 WP_117413092.1 DUF3126 family protein -
D1F64_RS15100 3299111..3299950 - 840 WP_117413093.1 serine O-acetyltransferase -
D1F64_RS15105 3300132..3301127 - 996 WP_162901585.1 hypothetical protein -
D1F64_RS15110 3301543..3302399 - 857 Protein_3036 alpha/beta hydrolase -
D1F64_RS15115 3302420..3303208 - 789 WP_117413095.1 alpha/beta hydrolase -
D1F64_RS15120 3303659..3303907 + 249 WP_117413096.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
D1F64_RS15125 3303911..3304198 + 288 WP_117413097.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D1F64_RS15130 3304323..3304592 + 270 WP_117414632.1 zinc-finger domain-containing protein -
D1F64_RS15135 3304604..3305794 + 1191 WP_117413098.1 FAD-dependent monooxygenase -
D1F64_RS15140 3305906..3306685 + 780 WP_117413099.1 competence/damage-inducible protein A -
D1F64_RS15145 3306750..3307256 + 507 WP_117413100.1 xanthine phosphoribosyltransferase -
D1F64_RS15150 3307357..3307716 + 360 WP_162901586.1 hypothetical protein -
D1F64_RS15155 3307812..3308480 + 669 WP_205470490.1 L,D-transpeptidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10991.70 Da        Isoelectric Point: 10.1822

>T110307 WP_117413097.1 NZ_CP031841:3303911-3304198 [Breoghania sp. L-A4]
MRLQFLPAARADLDAIFDYTVKQWGLAQAERYLRDMQATCESLRAGRIKGRSAEHVRSGYRKAASGSHMIYFKLADERLI
VVRILHQSMDVERHL

Download         Length: 288 bp

>T110307 NZ_CP031841:3303911-3304198 [Breoghania sp. L-A4]
ATGCGGCTCCAGTTTTTACCAGCCGCGAGAGCCGATCTGGACGCCATTTTTGATTACACTGTGAAACAATGGGGACTGGC
GCAGGCCGAGCGCTATCTTCGTGACATGCAGGCGACCTGTGAAAGTCTGCGCGCCGGTCGCATCAAGGGTCGCTCGGCCG
AGCACGTGCGCAGTGGCTACCGCAAGGCGGCGTCAGGATCTCACATGATCTATTTCAAACTGGCCGACGAGCGGCTCATC
GTCGTCCGCATCCTGCACCAGAGCATGGACGTCGAGCGGCATCTCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8657.50 Da        Isoelectric Point: 4.5388

>AT110307 WP_117413096.1 NZ_CP031841:3303659-3303907 [Breoghania sp. L-A4]
MSRNTSVSLGDHFAGFVDQSVKTGRYASASDVVRAGLRLLEEQEAKLDILRSALAAGETSGEPEDFDFDAYIAGKTSKST
GG

Download         Length: 249 bp

>AT110307 NZ_CP031841:3303659-3303907 [Breoghania sp. L-A4]
ATGTCCCGCAACACATCCGTCTCGCTGGGCGATCATTTCGCCGGCTTTGTCGACCAGAGTGTCAAGACCGGCCGATATGC
GAGCGCCAGCGATGTGGTGCGCGCAGGCCTCCGGCTGCTCGAAGAACAGGAAGCAAAGCTGGATATCCTGAGATCAGCAT
TGGCCGCCGGCGAAACCTCCGGCGAGCCGGAAGACTTCGATTTCGATGCCTACATCGCCGGGAAGACGTCAAAAAGCACG
GGCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References