Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2023657..2023928 Replicon chromosome
Accession NZ_CP031833
Organism Escherichia coli strain 2452

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2023787..2023890 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2023657..2023928 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0R13_RS10340 2020212..2020874 - 663 WP_001556661.1 exodeoxyribonuclease X -
D0R13_RS10345 2020898..2021554 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
D0R13_RS10350 2021656..2021886 - 231 WP_000916763.1 DNA polymerase III subunit theta -
D0R13_RS10355 2022025..2022399 + 375 WP_000168747.1 CopC domain-containing protein YobA -
D0R13_RS10360 2022403..2023275 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
D0R13_RS10365 2023288..2023629 + 342 WP_000976472.1 YebY family protein -
- 2023657..2023928 - 272 - - Antitoxin
- 2023787..2023890 + 104 - - Toxin
D0R13_RS10370 2024025..2024681 + 657 WP_001556660.1 protein-serine/threonine phosphatase -
D0R13_RS10375 2024682..2024873 - 192 WP_001338167.1 YebW family protein -
D0R13_RS10380 2024978..2025214 - 237 WP_001338166.1 DUF1480 family protein -
D0R13_RS10385 2025332..2026771 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T110254 NZ_CP031833:2023787-2023890 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT110254 NZ_CP031833:c2023928-2023657 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References